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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRMD4A
All Species:
11.21
Human Site:
S587
Identified Species:
35.24
UniProt:
Q9P2Q2
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2Q2
NP_060497.3
1039
115458
S587
N
R
P
P
P
P
Q
S
L
E
G
L
R
Q
M
Chimpanzee
Pan troglodytes
XP_001143334
1033
114918
S587
N
R
P
P
P
P
Q
S
L
E
G
L
R
Q
M
Rhesus Macaque
Macaca mulatta
XP_001086554
1182
133673
Y686
K
K
K
R
K
Q
D
Y
T
D
A
V
K
K
L
Dog
Lupus familis
XP_849159
1049
116776
S597
N
R
P
P
P
P
Q
S
L
E
G
L
R
Q
M
Cat
Felis silvestris
Mouse
Mus musculus
Q8BIE6
1020
113861
Q572
H
N
R
P
P
P
P
Q
S
L
E
G
L
R
Q
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510163
868
98664
S428
T
I
T
Y
D
D
A
S
D
M
L
N
L
P
G
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
O57457
619
70690
Q179
D
L
E
D
S
I
E
Q
I
H
K
T
L
L
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786842
1120
127484
R616
R
S
P
S
L
G
R
R
K
D
K
I
P
V
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
43.8
91.9
N.A.
96
N.A.
N.A.
40
N.A.
N.A.
22.1
N.A.
N.A.
N.A.
N.A.
34.4
Protein Similarity:
100
98.4
56.7
93.7
N.A.
96.9
N.A.
N.A.
52.8
N.A.
N.A.
34
N.A.
N.A.
N.A.
N.A.
51.5
P-Site Identity:
100
100
0
100
N.A.
20
N.A.
N.A.
6.6
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
40
100
N.A.
33.3
N.A.
N.A.
6.6
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
13
0
0
0
13
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
13
0
0
13
13
13
13
0
13
25
0
0
0
0
0
% D
% Glu:
0
0
13
0
0
0
13
0
0
38
13
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
13
0
0
0
0
38
13
0
0
25
% G
% His:
13
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% H
% Ile:
0
13
0
0
0
13
0
0
13
0
0
13
0
0
0
% I
% Lys:
13
13
13
0
13
0
0
0
13
0
25
0
13
13
0
% K
% Leu:
0
13
0
0
13
0
0
0
38
13
13
38
38
13
13
% L
% Met:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
38
% M
% Asn:
38
13
0
0
0
0
0
0
0
0
0
13
0
0
0
% N
% Pro:
0
0
50
50
50
50
13
0
0
0
0
0
13
13
0
% P
% Gln:
0
0
0
0
0
13
38
25
0
0
0
0
0
38
13
% Q
% Arg:
13
38
13
13
0
0
13
13
0
0
0
0
38
13
13
% R
% Ser:
0
13
0
13
13
0
0
50
13
0
0
0
0
0
0
% S
% Thr:
13
0
13
0
0
0
0
0
13
0
0
13
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
13
0
13
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
13
0
0
0
13
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _