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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRMD4A
All Species:
13.64
Human Site:
S681
Identified Species:
42.86
UniProt:
Q9P2Q2
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2Q2
NP_060497.3
1039
115458
S681
T
P
D
L
R
V
R
S
P
H
Y
V
H
S
T
Chimpanzee
Pan troglodytes
XP_001143334
1033
114918
S681
T
P
D
L
R
V
R
S
P
H
Y
V
H
S
T
Rhesus Macaque
Macaca mulatta
XP_001086554
1182
133673
Q780
R
K
S
S
I
N
E
Q
F
V
D
T
R
Q
S
Dog
Lupus familis
XP_849159
1049
116776
S691
T
P
D
L
R
V
R
S
P
H
Y
V
H
S
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8BIE6
1020
113861
S666
T
P
D
L
R
V
R
S
P
H
Y
V
H
S
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510163
868
98664
Q522
L
E
P
N
A
S
S
Q
H
S
R
Q
R
S
G
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
O57457
619
70690
F273
C
N
E
T
S
F
F
F
D
A
A
S
K
T
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786842
1120
127484
P710
D
G
S
T
R
S
Q
P
E
G
F
M
T
H
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
43.8
91.9
N.A.
96
N.A.
N.A.
40
N.A.
N.A.
22.1
N.A.
N.A.
N.A.
N.A.
34.4
Protein Similarity:
100
98.4
56.7
93.7
N.A.
96.9
N.A.
N.A.
52.8
N.A.
N.A.
34
N.A.
N.A.
N.A.
N.A.
51.5
P-Site Identity:
100
100
0
100
N.A.
100
N.A.
N.A.
6.6
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
6.6
100
N.A.
100
N.A.
N.A.
6.6
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
13
0
0
0
0
13
13
0
0
0
13
% A
% Cys:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
13
0
50
0
0
0
0
0
13
0
13
0
0
0
0
% D
% Glu:
0
13
13
0
0
0
13
0
13
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
13
13
13
13
0
13
0
0
0
0
% F
% Gly:
0
13
0
0
0
0
0
0
0
13
0
0
0
0
13
% G
% His:
0
0
0
0
0
0
0
0
13
50
0
0
50
13
0
% H
% Ile:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
13
0
0
0
0
0
0
0
0
0
0
13
0
0
% K
% Leu:
13
0
0
50
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% M
% Asn:
0
13
0
13
0
13
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
50
13
0
0
0
0
13
50
0
0
0
0
0
13
% P
% Gln:
0
0
0
0
0
0
13
25
0
0
0
13
0
13
0
% Q
% Arg:
13
0
0
0
63
0
50
0
0
0
13
0
25
0
0
% R
% Ser:
0
0
25
13
13
25
13
50
0
13
0
13
0
63
13
% S
% Thr:
50
0
0
25
0
0
0
0
0
0
0
13
13
13
50
% T
% Val:
0
0
0
0
0
50
0
0
0
13
0
50
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
50
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _