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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRMD4A
All Species:
16.97
Human Site:
Y206
Identified Species:
53.33
UniProt:
Q9P2Q2
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2Q2
NP_060497.3
1039
115458
Y206
R
G
Q
A
I
V
N
Y
M
S
I
V
E
S
L
Chimpanzee
Pan troglodytes
XP_001143334
1033
114918
Y206
R
G
Q
A
I
V
N
Y
M
S
I
V
E
S
L
Rhesus Macaque
Macaca mulatta
XP_001086554
1182
133673
K226
L
E
L
L
V
Q
P
K
L
L
A
R
E
L
L
Dog
Lupus familis
XP_849159
1049
116776
Y216
R
G
Q
A
I
V
N
Y
M
S
I
V
E
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BIE6
1020
113861
Y191
R
G
Q
A
I
V
N
Y
M
S
I
V
E
S
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510163
868
98664
I77
G
L
T
R
G
Q
A
I
V
Q
Y
M
K
V
V
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
O57457
619
70690
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786842
1120
127484
Y222
K
G
Q
C
I
V
C
Y
M
Q
L
V
E
G
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
43.8
91.9
N.A.
96
N.A.
N.A.
40
N.A.
N.A.
22.1
N.A.
N.A.
N.A.
N.A.
34.4
Protein Similarity:
100
98.4
56.7
93.7
N.A.
96.9
N.A.
N.A.
52.8
N.A.
N.A.
34
N.A.
N.A.
N.A.
N.A.
51.5
P-Site Identity:
100
100
13.3
100
N.A.
100
N.A.
N.A.
0
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
60
P-Site Similarity:
100
100
26.6
100
N.A.
100
N.A.
N.A.
26.6
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
50
0
0
13
0
0
0
13
0
0
0
0
% A
% Cys:
0
0
0
13
0
0
13
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
13
0
0
0
0
0
0
0
0
0
0
75
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
13
63
0
0
13
0
0
0
0
0
0
0
0
13
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
63
0
0
13
0
0
50
0
0
0
0
% I
% Lys:
13
0
0
0
0
0
0
13
0
0
0
0
13
0
0
% K
% Leu:
13
13
13
13
0
0
0
0
13
13
13
0
0
13
75
% L
% Met:
0
0
0
0
0
0
0
0
63
0
0
13
0
0
0
% M
% Asn:
0
0
0
0
0
0
50
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
63
0
0
25
0
0
0
25
0
0
0
0
0
% Q
% Arg:
50
0
0
13
0
0
0
0
0
0
0
13
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
50
0
0
0
50
0
% S
% Thr:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
13
63
0
0
13
0
0
63
0
13
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
63
0
0
13
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _