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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRMD4A
All Species:
16.67
Human Site:
Y500
Identified Species:
52.38
UniProt:
Q9P2Q2
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2Q2
NP_060497.3
1039
115458
Y500
K
K
Q
R
K
T
S
Y
L
N
A
L
K
K
L
Chimpanzee
Pan troglodytes
XP_001143334
1033
114918
Y500
K
K
Q
R
K
T
S
Y
L
N
A
L
K
K
L
Rhesus Macaque
Macaca mulatta
XP_001086554
1182
133673
E568
S
Q
D
S
E
V
S
E
E
Q
K
R
E
K
I
Dog
Lupus familis
XP_849159
1049
116776
Y510
K
K
Q
R
K
T
S
Y
L
N
A
L
K
K
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BIE6
1020
113861
Y485
K
K
Q
R
K
T
S
Y
L
N
A
L
K
K
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510163
868
98664
K347
S
N
F
I
I
Q
Q
K
L
V
E
A
A
K
K
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
O57457
619
70690
F98
T
L
Y
F
G
V
K
F
Y
A
E
D
P
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786842
1120
127484
Y519
R
K
T
R
R
E
S
Y
K
R
S
A
K
K
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
43.8
91.9
N.A.
96
N.A.
N.A.
40
N.A.
N.A.
22.1
N.A.
N.A.
N.A.
N.A.
34.4
Protein Similarity:
100
98.4
56.7
93.7
N.A.
96.9
N.A.
N.A.
52.8
N.A.
N.A.
34
N.A.
N.A.
N.A.
N.A.
51.5
P-Site Identity:
100
100
13.3
100
N.A.
100
N.A.
N.A.
13.3
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Similarity:
100
100
40
100
N.A.
100
N.A.
N.A.
13.3
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
13
50
25
13
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
13
0
0
0
0
0
0
0
0
13
0
0
0
% D
% Glu:
0
0
0
0
13
13
0
13
13
0
25
0
13
0
0
% E
% Phe:
0
0
13
13
0
0
0
13
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
13
0
0
0
0
0
0
0
0
13
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
13
13
0
0
0
0
0
0
0
0
0
13
% I
% Lys:
50
63
0
0
50
0
13
13
13
0
13
0
63
88
25
% K
% Leu:
0
13
0
0
0
0
0
0
63
0
0
50
0
0
63
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
13
0
0
0
0
0
0
0
50
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% P
% Gln:
0
13
50
0
0
13
13
0
0
13
0
0
0
0
0
% Q
% Arg:
13
0
0
63
13
0
0
0
0
13
0
13
0
0
0
% R
% Ser:
25
0
0
13
0
0
75
0
0
0
13
0
0
0
0
% S
% Thr:
13
0
13
0
0
50
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
25
0
0
0
13
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
13
0
0
0
0
63
13
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _