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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRMD4A
All Species:
6.67
Human Site:
Y821
Identified Species:
20.95
UniProt:
Q9P2Q2
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2Q2
NP_060497.3
1039
115458
Y821
G
G
A
G
G
G
V
Y
L
H
S
Q
S
Q
P
Chimpanzee
Pan troglodytes
XP_001143334
1033
114918
G815
G
G
A
G
G
A
G
G
A
G
G
G
V
Y
L
Rhesus Macaque
Macaca mulatta
XP_001086554
1182
133673
Y941
D
S
L
R
N
G
V
Y
S
K
S
Q
E
P
P
Dog
Lupus familis
XP_849159
1049
116776
G822
A
A
R
G
A
G
G
G
V
Y
L
H
S
Q
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BIE6
1020
113861
Y803
A
S
T
G
G
G
V
Y
L
H
S
Q
S
Q
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510163
868
98664
Y653
P
Y
A
E
N
D
L
Y
Y
N
G
G
Y
V
Y
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
O57457
619
70690
K404
S
A
S
V
Q
Q
E
K
P
S
A
P
W
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786842
1120
127484
N881
E
D
Q
Q
L
V
N
N
G
S
H
R
G
Q
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
43.8
91.9
N.A.
96
N.A.
N.A.
40
N.A.
N.A.
22.1
N.A.
N.A.
N.A.
N.A.
34.4
Protein Similarity:
100
98.4
56.7
93.7
N.A.
96.9
N.A.
N.A.
52.8
N.A.
N.A.
34
N.A.
N.A.
N.A.
N.A.
51.5
P-Site Identity:
100
33.3
40
26.6
N.A.
80
N.A.
N.A.
13.3
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
33.3
40
40
N.A.
80
N.A.
N.A.
26.6
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
25
38
0
13
13
0
0
13
0
13
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
13
13
0
0
0
13
0
0
0
0
0
0
0
0
0
% D
% Glu:
13
0
0
13
0
0
13
0
0
0
0
0
13
13
13
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
25
25
0
50
38
50
25
25
13
13
25
25
13
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
25
13
13
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
13
0
13
0
0
0
0
13
% K
% Leu:
0
0
13
0
13
0
13
0
25
0
13
0
0
0
13
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
25
0
13
13
0
13
0
0
0
0
0
% N
% Pro:
13
0
0
0
0
0
0
0
13
0
0
13
0
13
38
% P
% Gln:
0
0
13
13
13
13
0
0
0
0
0
38
0
50
0
% Q
% Arg:
0
0
13
13
0
0
0
0
0
0
0
13
0
0
0
% R
% Ser:
13
25
13
0
0
0
0
0
13
25
38
0
38
0
13
% S
% Thr:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
13
0
13
38
0
13
0
0
0
13
13
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% W
% Tyr:
0
13
0
0
0
0
0
50
13
13
0
0
13
13
13
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _