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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR8
All Species:
8.48
Human Site:
S281
Identified Species:
18.67
UniProt:
Q9P2S5
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2S5
NP_060288.3
460
51588
S281
V
Y
K
E
A
E
K
S
P
Q
L
G
L
G
C
Chimpanzee
Pan troglodytes
XP_001151905
460
51641
S281
V
Y
K
E
A
E
K
S
P
Q
L
G
L
G
C
Rhesus Macaque
Macaca mulatta
XP_001084011
461
51534
V282
L
E
H
V
G
S
E
V
G
L
A
L
A
C
P
Dog
Lupus familis
XP_536722
460
51757
N281
V
Y
K
E
A
E
K
N
P
R
L
A
L
G
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9JM98
462
52008
S281
V
Y
K
E
A
E
K
S
P
L
L
G
L
G
H
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506726
450
50849
C281
V
Y
K
E
T
E
K
C
P
T
L
G
L
E
N
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6GMD2
305
33316
E141
G
V
E
T
G
K
K
E
Y
S
L
D
T
R
G
Zebra Danio
Brachydanio rerio
NP_956187
446
50971
R281
V
F
K
E
V
E
K
R
P
V
V
S
E
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001193137
396
44809
V233
I
G
S
Y
D
Q
K
V
R
V
L
N
H
I
T
Poplar Tree
Populus trichocarpa
XP_002297923
338
38049
F175
E
L
C
L
S
D
E
F
L
Q
G
N
S
D
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22785
525
56709
Q346
S
S
G
S
C
L
A
Q
V
S
D
D
S
K
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
93.4
89.7
N.A.
88.3
N.A.
N.A.
83.4
N.A.
20
70.2
N.A.
N.A.
N.A.
N.A.
54.5
Protein Similarity:
100
99.3
94.3
95.2
N.A.
93.7
N.A.
N.A.
91
N.A.
37.1
81
N.A.
N.A.
N.A.
N.A.
69.5
P-Site Identity:
100
100
0
73.3
N.A.
86.6
N.A.
N.A.
66.6
N.A.
13.3
40
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
13.3
86.6
N.A.
86.6
N.A.
N.A.
66.6
N.A.
26.6
53.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
33
N.A.
N.A.
20.5
N.A.
N.A.
Protein Similarity:
45.2
N.A.
N.A.
33.7
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
37
0
10
0
0
0
10
10
10
0
0
% A
% Cys:
0
0
10
0
10
0
0
10
0
0
0
0
0
10
19
% C
% Asp:
0
0
0
0
10
10
0
0
0
0
10
19
0
19
0
% D
% Glu:
10
10
10
55
0
55
19
10
0
0
0
0
10
10
0
% E
% Phe:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
10
10
10
0
19
0
0
0
10
0
10
37
0
37
10
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
0
10
0
10
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
0
0
55
0
0
10
73
0
0
0
0
0
0
10
0
% K
% Leu:
10
10
0
10
0
10
0
0
10
19
64
10
46
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
19
0
0
19
% N
% Pro:
0
0
0
0
0
0
0
0
55
0
0
0
0
0
10
% P
% Gln:
0
0
0
0
0
10
0
10
0
28
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
10
10
10
0
0
0
10
10
% R
% Ser:
10
10
10
10
10
10
0
28
0
19
0
10
19
0
0
% S
% Thr:
0
0
0
10
10
0
0
0
0
10
0
0
10
0
10
% T
% Val:
55
10
0
10
10
0
0
19
10
19
10
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
46
0
10
0
0
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _