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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WDR8 All Species: 20.61
Human Site: S407 Identified Species: 45.33
UniProt: Q9P2S5 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P2S5 NP_060288.3 460 51588 S407 W S P A G C M S V Q V P G E G
Chimpanzee Pan troglodytes XP_001151905 460 51641 S407 W S P A G C M S V Q V P G E G
Rhesus Macaque Macaca mulatta XP_001084011 461 51534 S408 W S P A G C M S V Q V P G E G
Dog Lupus familis XP_536722 460 51757 S407 W S P A G C V S V Q V P G E G
Cat Felis silvestris
Mouse Mus musculus Q9JM98 462 52008 S407 W S P A G C V S V Q V P G E G
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506726 450 50849 Y398 C T G N S K V Y L W S P A G C
Chicken Gallus gallus
Frog Xenopus laevis Q6GMD2 305 33316 D253 H F V S S S S D K S V K V W D
Zebra Danio Brachydanio rerio NP_956187 446 50971 K394 A L C T G N T K L Y M W S P A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001193137 396 44809 V344 N A L W I W D V Q K L S Q A A
Poplar Tree Populus trichocarpa XP_002297923 338 38049 S286 H L Y M W T P S G A Y C V S N
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O22785 525 56709 Y459 A A S D I K V Y Q T A S V K A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 93.4 89.7 N.A. 88.3 N.A. N.A. 83.4 N.A. 20 70.2 N.A. N.A. N.A. N.A. 54.5
Protein Similarity: 100 99.3 94.3 95.2 N.A. 93.7 N.A. N.A. 91 N.A. 37.1 81 N.A. N.A. N.A. N.A. 69.5
P-Site Identity: 100 100 100 93.3 N.A. 93.3 N.A. N.A. 6.6 N.A. 6.6 6.6 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 100 N.A. N.A. 26.6 N.A. 13.3 20 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: 33 N.A. N.A. 20.5 N.A. N.A.
Protein Similarity: 45.2 N.A. N.A. 33.7 N.A. N.A.
P-Site Identity: 6.6 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 6.6 N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 19 19 0 46 0 0 0 0 0 10 10 0 10 10 28 % A
% Cys: 10 0 10 0 0 46 0 0 0 0 0 10 0 0 10 % C
% Asp: 0 0 0 10 0 0 10 10 0 0 0 0 0 0 10 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 46 0 % E
% Phe: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 10 0 55 0 0 0 10 0 0 0 46 10 46 % G
% His: 19 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 19 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 19 0 10 10 10 0 10 0 10 0 % K
% Leu: 0 19 10 0 0 0 0 0 19 0 10 0 0 0 0 % L
% Met: 0 0 0 10 0 0 28 0 0 0 10 0 0 0 0 % M
% Asn: 10 0 0 10 0 10 0 0 0 0 0 0 0 0 10 % N
% Pro: 0 0 46 0 0 0 10 0 0 0 0 55 0 10 0 % P
% Gln: 0 0 0 0 0 0 0 0 19 46 0 0 10 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 46 10 10 19 10 10 55 0 10 10 19 10 10 0 % S
% Thr: 0 10 0 10 0 10 10 0 0 10 0 0 0 0 0 % T
% Val: 0 0 10 0 0 0 37 10 46 0 55 0 28 0 0 % V
% Trp: 46 0 0 10 10 10 0 0 0 10 0 10 0 10 0 % W
% Tyr: 0 0 10 0 0 0 0 19 0 10 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _