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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STX18
All Species:
22.42
Human Site:
S191
Identified Species:
37.95
UniProt:
Q9P2W9
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2W9
NP_058626.1
335
38674
S191
E
K
V
S
Q
S
P
S
K
D
S
E
E
N
P
Chimpanzee
Pan troglodytes
XP_001154387
335
38724
S191
E
K
V
S
Q
S
P
S
K
D
S
E
E
N
P
Rhesus Macaque
Macaca mulatta
XP_001094903
335
38636
S191
E
K
V
S
Q
S
P
S
K
D
S
E
E
N
P
Dog
Lupus familis
XP_851021
336
38679
S192
E
K
V
S
Q
T
P
S
Q
E
S
E
E
K
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8VDS8
334
38363
S190
E
K
A
P
Q
N
A
S
Q
D
S
E
G
K
P
Rat
Rattus norvegicus
Q68FW4
334
38494
S190
E
K
S
S
H
N
A
S
Q
D
S
E
E
K
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089679
372
42507
K190
Q
L
D
T
G
A
E
K
K
S
A
D
D
E
N
Zebra Danio
Brachydanio rerio
Q4VBI7
314
36223
V189
G
E
E
N
D
K
P
V
S
D
G
N
V
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524485
395
45117
T251
A
N
Q
H
K
P
R
T
R
K
R
S
K
A
N
Honey Bee
Apis mellifera
XP_623865
296
34345
N176
P
M
K
I
Q
E
I
N
G
D
V
N
T
L
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782212
312
36043
N188
G
D
D
Q
V
K
N
N
P
P
L
D
L
H
L
Poplar Tree
Populus trichocarpa
XP_002316241
311
35519
T189
S
S
V
D
S
S
K
T
N
N
L
D
F
M
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P59277
310
35555
N189
P
I
N
T
T
L
G
N
S
E
S
I
E
P
D
Baker's Yeast
Sacchar. cerevisiae
P36116
164
18893
G44
G
R
Q
E
A
R
I
G
E
K
A
S
E
A
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.6
95.2
N.A.
92.5
92.8
N.A.
N.A.
N.A.
62.6
70.4
N.A.
32.4
46.8
N.A.
48.9
Protein Similarity:
100
99.6
99.6
97.9
N.A.
96.1
96.1
N.A.
N.A.
N.A.
71.5
80.3
N.A.
51.9
66.2
N.A.
64.1
P-Site Identity:
100
100
100
73.3
N.A.
53.3
60
N.A.
N.A.
N.A.
6.6
13.3
N.A.
0
13.3
N.A.
0
P-Site Similarity:
100
100
100
93.3
N.A.
66.6
73.3
N.A.
N.A.
N.A.
46.6
33.3
N.A.
26.6
20
N.A.
20
Percent
Protein Identity:
25
N.A.
N.A.
24.1
20.9
N.A.
Protein Similarity:
46.2
N.A.
N.A.
47.7
32.8
N.A.
P-Site Identity:
13.3
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
33.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
8
8
15
0
0
0
15
0
0
15
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
15
8
8
0
0
0
0
50
0
22
8
8
8
% D
% Glu:
43
8
8
8
0
8
8
0
8
15
0
43
50
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
22
0
0
0
8
0
8
8
8
0
8
0
8
0
0
% G
% His:
0
0
0
8
8
0
0
0
0
0
0
0
0
8
8
% H
% Ile:
0
8
0
8
0
0
15
0
0
0
0
8
0
0
8
% I
% Lys:
0
43
8
0
8
15
8
8
29
15
0
0
8
22
0
% K
% Leu:
0
8
0
0
0
8
0
0
0
0
15
0
8
8
15
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
8
8
8
0
15
8
22
8
8
0
15
0
22
15
% N
% Pro:
15
0
0
8
0
8
36
0
8
8
0
0
0
8
43
% P
% Gln:
8
0
15
8
43
0
0
0
22
0
0
0
0
0
0
% Q
% Arg:
0
8
0
0
0
8
8
0
8
0
8
0
0
0
0
% R
% Ser:
8
8
8
36
8
29
0
43
15
8
50
15
0
0
0
% S
% Thr:
0
0
0
15
8
8
0
15
0
0
0
0
8
0
0
% T
% Val:
0
0
36
0
8
0
0
8
0
0
8
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _