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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STX18
All Species:
27.88
Human Site:
S248
Identified Species:
47.18
UniProt:
Q9P2W9
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2W9
NP_058626.1
335
38674
S248
R
L
I
G
E
M
N
S
L
F
D
E
V
R
Q
Chimpanzee
Pan troglodytes
XP_001154387
335
38724
S248
R
L
I
G
E
M
N
S
L
F
D
E
V
R
Q
Rhesus Macaque
Macaca mulatta
XP_001094903
335
38636
S248
R
L
I
G
E
M
N
S
L
F
D
E
V
R
Q
Dog
Lupus familis
XP_851021
336
38679
S249
R
L
I
G
E
M
N
S
L
F
D
E
V
R
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8VDS8
334
38363
S247
R
L
I
G
E
M
N
S
L
F
D
E
V
R
Q
Rat
Rattus norvegicus
Q68FW4
334
38494
S247
R
L
I
G
E
M
N
S
L
F
D
E
V
R
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089679
372
42507
S242
R
L
V
S
E
M
N
S
L
F
D
E
V
R
Q
Zebra Danio
Brachydanio rerio
Q4VBI7
314
36223
E241
Q
I
E
G
K
V
V
E
I
S
R
L
Q
E
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524485
395
45117
G308
H
I
Y
N
F
L
Q
G
V
S
E
E
V
E
Q
Honey Bee
Apis mellifera
XP_623865
296
34345
Q228
V
V
H
I
A
E
L
Q
E
I
F
T
E
K
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782212
312
36043
E240
Q
I
E
G
K
V
V
E
I
A
Q
L
Q
E
I
Poplar Tree
Populus trichocarpa
XP_002316241
311
35519
S241
E
T
K
M
V
E
M
S
A
L
N
H
L
M
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P59277
310
35555
A241
T
K
M
V
E
M
S
A
L
N
H
L
M
A
T
Baker's Yeast
Sacchar. cerevisiae
P36116
164
18893
K96
E
D
A
E
E
E
I
K
N
L
P
F
K
R
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.6
95.2
N.A.
92.5
92.8
N.A.
N.A.
N.A.
62.6
70.4
N.A.
32.4
46.8
N.A.
48.9
Protein Similarity:
100
99.6
99.6
97.9
N.A.
96.1
96.1
N.A.
N.A.
N.A.
71.5
80.3
N.A.
51.9
66.2
N.A.
64.1
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
N.A.
86.6
6.6
N.A.
20
0
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
N.A.
93.3
40
N.A.
46.6
13.3
N.A.
40
Percent
Protein Identity:
25
N.A.
N.A.
24.1
20.9
N.A.
Protein Similarity:
46.2
N.A.
N.A.
47.7
32.8
N.A.
P-Site Identity:
6.6
N.A.
N.A.
20
13.3
N.A.
P-Site Similarity:
20
N.A.
N.A.
46.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
0
0
8
8
8
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
0
0
50
0
0
0
0
% D
% Glu:
15
0
15
8
65
22
0
15
8
0
8
58
8
22
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
50
8
8
0
0
0
% F
% Gly:
0
0
0
58
0
0
0
8
0
0
0
0
0
0
0
% G
% His:
8
0
8
0
0
0
0
0
0
0
8
8
0
0
0
% H
% Ile:
0
22
43
8
0
0
8
0
15
8
0
0
0
0
15
% I
% Lys:
0
8
8
0
15
0
0
8
0
0
0
0
8
8
0
% K
% Leu:
0
50
0
0
0
8
8
0
58
15
0
22
8
0
8
% L
% Met:
0
0
8
8
0
58
8
0
0
0
0
0
8
8
0
% M
% Asn:
0
0
0
8
0
0
50
0
8
8
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% P
% Gln:
15
0
0
0
0
0
8
8
0
0
8
0
15
0
58
% Q
% Arg:
50
0
0
0
0
0
0
0
0
0
8
0
0
58
0
% R
% Ser:
0
0
0
8
0
0
8
58
0
15
0
0
0
0
8
% S
% Thr:
8
8
0
0
0
0
0
0
0
0
0
8
0
0
8
% T
% Val:
8
8
8
8
8
15
15
0
8
0
0
0
58
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _