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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: STX18 All Species: 23.94
Human Site: S42 Identified Species: 40.51
UniProt: Q9P2W9 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P2W9 NP_058626.1 335 38674 S42 R D E L F R R S P R P K G D F
Chimpanzee Pan troglodytes XP_001154387 335 38724 S42 R D E L F R R S P R P K G D F
Rhesus Macaque Macaca mulatta XP_001094903 335 38636 S42 R D E L F R R S P R P K G D F
Dog Lupus familis XP_851021 336 38679 S43 R D E L F R R S P R P K G D F
Cat Felis silvestris
Mouse Mus musculus Q8VDS8 334 38363 S42 R D E L F R R S P R P K G D F
Rat Rattus norvegicus Q68FW4 334 38494 S42 R D E L F R R S P R P K G D F
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001089679 372 42507 S43 R L P R G E F S G K A R E V I
Zebra Danio Brachydanio rerio Q4VBI7 314 36223 R41 P G A Q K R P R P R Q R D S F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524485 395 45117 A48 K D D F A K Q A K E V C N K I
Honey Bee Apis mellifera XP_623865 296 34345 I30 I I D N T Q N I K K A K N K S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782212 312 36043 G41 V Y I R S P G G A R A R Y Y F
Poplar Tree Populus trichocarpa XP_002316241 311 35519 Q43 F I I H K P R Q R S P F T K A
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P59277 310 35555 E43 F I I H K P K E R S P F T K A
Baker's Yeast Sacchar. cerevisiae P36116 164 18893
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 99.6 95.2 N.A. 92.5 92.8 N.A. N.A. N.A. 62.6 70.4 N.A. 32.4 46.8 N.A. 48.9
Protein Similarity: 100 99.6 99.6 97.9 N.A. 96.1 96.1 N.A. N.A. N.A. 71.5 80.3 N.A. 51.9 66.2 N.A. 64.1
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. N.A. 13.3 26.6 N.A. 6.6 6.6 N.A. 13.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. N.A. 26.6 33.3 N.A. 40 26.6 N.A. 20
Percent
Protein Identity: 25 N.A. N.A. 24.1 20.9 N.A.
Protein Similarity: 46.2 N.A. N.A. 47.7 32.8 N.A.
P-Site Identity: 13.3 N.A. N.A. 6.6 0 N.A.
P-Site Similarity: 13.3 N.A. N.A. 13.3 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 8 0 0 8 8 0 22 0 0 0 15 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 0 50 15 0 0 0 0 0 0 0 0 0 8 43 0 % D
% Glu: 0 0 43 0 0 8 0 8 0 8 0 0 8 0 0 % E
% Phe: 15 0 0 8 43 0 8 0 0 0 0 15 0 0 58 % F
% Gly: 0 8 0 0 8 0 8 8 8 0 0 0 43 0 0 % G
% His: 0 0 0 15 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 22 22 0 0 0 0 8 0 0 0 0 0 0 15 % I
% Lys: 8 0 0 0 22 8 8 0 15 15 0 50 0 29 0 % K
% Leu: 0 8 0 43 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 0 0 8 0 0 0 0 0 15 0 0 % N
% Pro: 8 0 8 0 0 22 8 0 50 0 58 0 0 0 0 % P
% Gln: 0 0 0 8 0 8 8 8 0 0 8 0 0 0 0 % Q
% Arg: 50 0 0 15 0 50 50 8 15 58 0 22 0 0 0 % R
% Ser: 0 0 0 0 8 0 0 50 0 15 0 0 0 8 8 % S
% Thr: 0 0 0 0 8 0 0 0 0 0 0 0 15 0 0 % T
% Val: 8 0 0 0 0 0 0 0 0 0 8 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 0 0 0 0 0 8 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _