KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STX18
All Species:
23.94
Human Site:
S51
Identified Species:
40.51
UniProt:
Q9P2W9
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2W9
NP_058626.1
335
38674
S51
R
P
K
G
D
F
S
S
R
A
R
E
V
I
S
Chimpanzee
Pan troglodytes
XP_001154387
335
38724
S51
R
P
K
G
D
F
S
S
R
A
R
E
V
I
S
Rhesus Macaque
Macaca mulatta
XP_001094903
335
38636
S51
R
P
K
G
D
F
S
S
R
A
R
E
V
I
S
Dog
Lupus familis
XP_851021
336
38679
S52
R
P
K
G
D
F
S
S
R
A
R
E
V
I
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8VDS8
334
38363
S51
R
P
K
G
D
F
S
S
R
A
R
E
V
I
S
Rat
Rattus norvegicus
Q68FW4
334
38494
S51
R
P
K
G
D
F
S
S
R
A
R
E
V
I
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089679
372
42507
N52
K
A
R
E
V
I
I
N
I
G
K
L
K
D
F
Zebra Danio
Brachydanio rerio
Q4VBI7
314
36223
C50
R
Q
R
D
S
F
S
C
K
A
R
E
V
I
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524485
395
45117
S57
E
V
C
N
K
I
T
S
L
R
N
V
L
I
E
Honey Bee
Apis mellifera
XP_623865
296
34345
F39
K
A
K
N
K
S
A
F
F
I
K
V
Q
G
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782212
312
36043
R50
R
A
R
Y
Y
F
N
R
K
N
R
Y
S
I
D
Poplar Tree
Populus trichocarpa
XP_002316241
311
35519
L52
S
P
F
T
K
A
A
L
K
T
L
E
S
I
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P59277
310
35555
F52
S
P
F
T
K
A
A
F
K
T
L
D
S
I
K
Baker's Yeast
Sacchar. cerevisiae
P36116
164
18893
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.6
95.2
N.A.
92.5
92.8
N.A.
N.A.
N.A.
62.6
70.4
N.A.
32.4
46.8
N.A.
48.9
Protein Similarity:
100
99.6
99.6
97.9
N.A.
96.1
96.1
N.A.
N.A.
N.A.
71.5
80.3
N.A.
51.9
66.2
N.A.
64.1
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
N.A.
0
60
N.A.
13.3
6.6
N.A.
26.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
N.A.
26.6
73.3
N.A.
26.6
26.6
N.A.
46.6
Percent
Protein Identity:
25
N.A.
N.A.
24.1
20.9
N.A.
Protein Similarity:
46.2
N.A.
N.A.
47.7
32.8
N.A.
P-Site Identity:
20
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
33.3
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
22
0
0
0
15
22
0
0
50
0
0
0
0
0
% A
% Cys:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
43
0
0
0
0
0
0
8
0
8
8
% D
% Glu:
8
0
0
8
0
0
0
0
0
0
0
58
0
0
8
% E
% Phe:
0
0
15
0
0
58
0
15
8
0
0
0
0
0
8
% F
% Gly:
0
0
0
43
0
0
0
0
0
8
0
0
0
8
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
15
8
0
8
8
0
0
0
79
0
% I
% Lys:
15
0
50
0
29
0
0
0
29
0
15
0
8
0
8
% K
% Leu:
0
0
0
0
0
0
0
8
8
0
15
8
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
15
0
0
8
8
0
8
8
0
0
0
0
% N
% Pro:
0
58
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% Q
% Arg:
58
0
22
0
0
0
0
8
43
8
58
0
0
0
0
% R
% Ser:
15
0
0
0
8
8
50
50
0
0
0
0
22
0
50
% S
% Thr:
0
0
0
15
0
0
8
0
0
15
0
0
0
0
0
% T
% Val:
0
8
0
0
8
0
0
0
0
0
0
15
50
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
8
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _