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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: STX18 All Species: 31.52
Human Site: T18 Identified Species: 53.33
UniProt: Q9P2W9 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P2W9 NP_058626.1 335 38674 T18 A S V K T V K T R N K A L G V
Chimpanzee Pan troglodytes XP_001154387 335 38724 T18 A R V K T V K T R N K A L G V
Rhesus Macaque Macaca mulatta XP_001094903 335 38636 T18 A S V K T V K T R N K A L G V
Dog Lupus familis XP_851021 336 38679 T18 A S V K T V K T R N K A L G V
Cat Felis silvestris
Mouse Mus musculus Q8VDS8 334 38363 T18 A S V K T V K T R N K A L G V
Rat Rattus norvegicus Q68FW4 334 38494 T18 A S V K T V K T R N K A L G V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001089679 372 42507 T18 A S V K T V K T R N K A L G V
Zebra Danio Brachydanio rerio Q4VBI7 314 36223 T18 A S V K T V K T R N K A L G L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524485 395 45117 R18 V M T V R L Q R K A E L A G K
Honey Bee Apis mellifera XP_623865 296 34345
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782212 312 36043 F18 V T T I Q K Q F F Q Y C R F P
Poplar Tree Populus trichocarpa XP_002316241 311 35519 V20 D A V R H T A V S L G Y N E A
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P59277 310 35555 V20 D S V R N S A V S I G Y N E S
Baker's Yeast Sacchar. cerevisiae P36116 164 18893
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 99.6 95.2 N.A. 92.5 92.8 N.A. N.A. N.A. 62.6 70.4 N.A. 32.4 46.8 N.A. 48.9
Protein Similarity: 100 99.6 99.6 97.9 N.A. 96.1 96.1 N.A. N.A. N.A. 71.5 80.3 N.A. 51.9 66.2 N.A. 64.1
P-Site Identity: 100 93.3 100 100 N.A. 100 100 N.A. N.A. N.A. 100 93.3 N.A. 6.6 0 N.A. 0
P-Site Similarity: 100 93.3 100 100 N.A. 100 100 N.A. N.A. N.A. 100 100 N.A. 33.3 0 N.A. 13.3
Percent
Protein Identity: 25 N.A. N.A. 24.1 20.9 N.A.
Protein Similarity: 46.2 N.A. N.A. 47.7 32.8 N.A.
P-Site Identity: 6.6 N.A. N.A. 13.3 0 N.A.
P-Site Similarity: 20 N.A. N.A. 20 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 58 8 0 0 0 0 15 0 0 8 0 58 8 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 15 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 8 0 0 15 0 % E
% Phe: 0 0 0 0 0 0 0 8 8 0 0 0 0 8 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 15 0 0 65 0 % G
% His: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 8 0 0 0 0 0 8 0 0 0 0 0 % I
% Lys: 0 0 0 58 0 8 58 0 8 0 58 0 0 0 8 % K
% Leu: 0 0 0 0 0 8 0 0 0 8 0 8 58 0 8 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 8 0 0 0 0 58 0 0 15 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % P
% Gln: 0 0 0 0 8 0 15 0 0 8 0 0 0 0 0 % Q
% Arg: 0 8 0 15 8 0 0 8 58 0 0 0 8 0 0 % R
% Ser: 0 58 0 0 0 8 0 0 15 0 0 0 0 0 8 % S
% Thr: 0 8 15 0 58 8 0 58 0 0 0 0 0 0 0 % T
% Val: 15 0 72 8 0 58 0 15 0 0 0 0 0 0 50 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 8 15 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _