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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: STX18 All Species: 29.39
Human Site: T91 Identified Species: 49.74
UniProt: Q9P2W9 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P2W9 NP_058626.1 335 38674 T91 E Y G R M T D T E R D Q I D Q
Chimpanzee Pan troglodytes XP_001154387 335 38724 T91 E Y G R M T D T E R D Q I D Q
Rhesus Macaque Macaca mulatta XP_001094903 335 38636 T91 E Y G R M T D T E R D Q I D Q
Dog Lupus familis XP_851021 336 38679 T92 E Y G R M T D T E R D Q I D Q
Cat Felis silvestris
Mouse Mus musculus Q8VDS8 334 38363 T91 D Y G R M T D T E R D Q I D Q
Rat Rattus norvegicus Q68FW4 334 38494 T91 E Y G R M T D T E R D Q I D Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001089679 372 42507 D92 E R D Q I D Q D A Q I F M R T
Zebra Danio Brachydanio rerio Q4VBI7 314 36223 S90 E V S R M T D S E R D Q I D Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524485 395 45117 A106 T F Y T Q H L A K M R S D W K
Honey Bee Apis mellifera XP_623865 296 34345 T78 M S N I P S M T D A D R D K I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782212 312 36043 D89 H M S D A E R D Q I D S D A Q
Poplar Tree Populus trichocarpa XP_002316241 311 35519 T91 D S I E Q E V T A F I K A C K
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P59277 310 35555 A91 D S I E Q E V A A F I K A C K
Baker's Yeast Sacchar. cerevisiae P36116 164 18893
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 99.6 95.2 N.A. 92.5 92.8 N.A. N.A. N.A. 62.6 70.4 N.A. 32.4 46.8 N.A. 48.9
Protein Similarity: 100 99.6 99.6 97.9 N.A. 96.1 96.1 N.A. N.A. N.A. 71.5 80.3 N.A. 51.9 66.2 N.A. 64.1
P-Site Identity: 100 100 100 100 N.A. 93.3 100 N.A. N.A. N.A. 6.6 80 N.A. 0 13.3 N.A. 13.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. N.A. 33.3 86.6 N.A. 20 33.3 N.A. 20
Percent
Protein Identity: 25 N.A. N.A. 24.1 20.9 N.A.
Protein Similarity: 46.2 N.A. N.A. 47.7 32.8 N.A.
P-Site Identity: 6.6 N.A. N.A. 0 0 N.A.
P-Site Similarity: 26.6 N.A. N.A. 20 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 0 0 15 22 8 0 0 15 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 15 0 % C
% Asp: 22 0 8 8 0 8 50 15 8 0 65 0 22 50 0 % D
% Glu: 50 0 0 15 0 22 0 0 50 0 0 0 0 0 0 % E
% Phe: 0 8 0 0 0 0 0 0 0 15 0 8 0 0 0 % F
% Gly: 0 0 43 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 8 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 15 8 8 0 0 0 0 8 22 0 50 0 8 % I
% Lys: 0 0 0 0 0 0 0 0 8 0 0 15 0 8 22 % K
% Leu: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % L
% Met: 8 8 0 0 50 0 8 0 0 8 0 0 8 0 0 % M
% Asn: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 8 22 0 8 0 8 8 0 50 0 0 58 % Q
% Arg: 0 8 0 50 0 0 8 0 0 50 8 8 0 8 0 % R
% Ser: 0 22 15 0 0 8 0 8 0 0 0 15 0 0 0 % S
% Thr: 8 0 0 8 0 50 0 58 0 0 0 0 0 0 8 % T
% Val: 0 8 0 0 0 0 15 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % W
% Tyr: 0 43 8 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _