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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STX18
All Species:
26.06
Human Site:
Y74
Identified Species:
44.1
UniProt:
Q9P2W9
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2W9
NP_058626.1
335
38674
Y74
L
L
E
H
R
K
D
Y
I
N
A
Y
S
H
T
Chimpanzee
Pan troglodytes
XP_001154387
335
38724
Y74
L
L
E
H
R
K
D
Y
I
N
A
Y
S
H
T
Rhesus Macaque
Macaca mulatta
XP_001094903
335
38636
Y74
L
L
E
H
R
K
D
Y
I
N
A
Y
S
H
T
Dog
Lupus familis
XP_851021
336
38679
Y75
L
L
E
H
R
K
D
Y
I
N
A
Y
S
H
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8VDS8
334
38363
Y74
L
L
E
H
R
K
E
Y
I
N
A
Y
S
H
T
Rat
Rattus norvegicus
Q68FW4
334
38494
Y74
L
L
E
H
R
K
E
Y
I
N
A
Y
S
H
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089679
372
42507
V75
I
N
A
C
S
H
V
V
S
E
Y
S
C
M
T
Zebra Danio
Brachydanio rerio
Q4VBI7
314
36223
Y73
L
L
Q
H
R
K
D
Y
V
N
A
G
S
V
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524485
395
45117
L89
M
T
D
A
Q
R
D
L
I
D
R
E
S
E
K
Honey Bee
Apis mellifera
XP_623865
296
34345
R61
R
E
F
L
L
E
N
R
K
A
Y
L
N
F
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782212
312
36043
V72
A
G
K
I
T
S
I
V
A
S
H
L
V
N
D
Poplar Tree
Populus trichocarpa
XP_002316241
311
35519
D74
K
H
R
K
D
Y
V
D
L
H
R
T
T
E
Q
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P59277
310
35555
D74
K
H
R
K
D
Y
V
D
L
H
R
T
T
E
Q
Baker's Yeast
Sacchar. cerevisiae
P36116
164
18893
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.6
95.2
N.A.
92.5
92.8
N.A.
N.A.
N.A.
62.6
70.4
N.A.
32.4
46.8
N.A.
48.9
Protein Similarity:
100
99.6
99.6
97.9
N.A.
96.1
96.1
N.A.
N.A.
N.A.
71.5
80.3
N.A.
51.9
66.2
N.A.
64.1
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
N.A.
6.6
66.6
N.A.
20
0
N.A.
0
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
N.A.
N.A.
13.3
80
N.A.
53.3
26.6
N.A.
20
Percent
Protein Identity:
25
N.A.
N.A.
24.1
20.9
N.A.
Protein Similarity:
46.2
N.A.
N.A.
47.7
32.8
N.A.
P-Site Identity:
0
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
20
N.A.
N.A.
20
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
8
0
0
0
0
8
8
50
0
0
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
8
0
15
0
43
15
0
8
0
0
0
0
8
% D
% Glu:
0
8
43
0
0
8
15
0
0
8
0
8
0
22
0
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% G
% His:
0
15
0
50
0
8
0
0
0
15
8
0
0
43
0
% H
% Ile:
8
0
0
8
0
0
8
0
50
0
0
0
0
0
8
% I
% Lys:
15
0
8
15
0
50
0
0
8
0
0
0
0
0
8
% K
% Leu:
50
50
0
8
8
0
0
8
15
0
0
15
0
0
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% M
% Asn:
0
8
0
0
0
0
8
0
0
50
0
0
8
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
15
% Q
% Arg:
8
0
15
0
50
8
0
8
0
0
22
0
0
0
0
% R
% Ser:
0
0
0
0
8
8
0
0
8
8
0
8
58
0
8
% S
% Thr:
0
8
0
0
8
0
0
0
0
0
0
15
15
0
43
% T
% Val:
0
0
0
0
0
0
22
15
8
0
0
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
15
0
50
0
0
15
43
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _