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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IMPACT
All Species:
39.7
Human Site:
Y222
Identified Species:
72.78
UniProt:
Q9P2X3
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2X3
NP_060909.1
320
36462
Y222
A
T
H
N
I
Y
A
Y
R
I
Y
C
E
D
K
Chimpanzee
Pan troglodytes
XP_512067
435
49229
Y313
A
T
H
N
I
Y
A
Y
R
I
Y
C
E
D
K
Rhesus Macaque
Macaca mulatta
XP_001095925
441
49979
Y343
A
T
H
N
I
Y
A
Y
R
I
Y
C
E
D
K
Dog
Lupus familis
XP_547635
301
34181
Y220
A
T
H
N
I
Y
A
Y
R
I
Y
C
E
D
K
Cat
Felis silvestris
Mouse
Mus musculus
O55091
318
36258
Y221
A
T
H
N
I
Y
A
Y
R
I
F
C
E
D
K
Rat
Rattus norvegicus
Q5GFD9
317
35976
Y220
A
T
H
N
I
Y
A
Y
R
I
Y
C
E
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514470
160
18360
K92
H
Q
P
E
D
A
V
K
T
L
D
F
V
I
P
Chicken
Gallus gallus
XP_419166
320
36678
Y221
A
T
H
N
I
Y
A
Y
R
I
Y
C
E
D
K
Frog
Xenopus laevis
Q9W625
312
35622
Y219
A
T
H
N
I
Y
A
Y
R
I
Y
I
K
E
R
Zebra Danio
Brachydanio rerio
Q642J4
317
35883
Y222
A
T
H
N
I
Y
A
Y
R
I
Y
C
Q
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XWF4
257
29581
I189
T
E
I
N
G
K
P
I
H
H
H
D
C
V
D
Sea Urchin
Strong. purpuratus
XP_001182599
316
35766
Y239
A
T
H
N
V
M
A
Y
R
I
Y
K
E
D
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P25637
258
28999
G190
A
W
R
I
K
Q
D
G
S
A
A
T
Y
Q
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.2
71.8
89.3
N.A.
82.1
83.1
N.A.
37.5
70.9
60
63.7
N.A.
N.A.
N.A.
35.9
45.6
Protein Similarity:
100
72.4
72.5
92.1
N.A.
91.5
90.6
N.A.
44.6
84.3
78.1
77.8
N.A.
N.A.
N.A.
52.8
63.1
P-Site Identity:
100
100
100
100
N.A.
93.3
100
N.A.
0
100
73.3
86.6
N.A.
N.A.
N.A.
6.6
73.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
6.6
100
93.3
100
N.A.
N.A.
N.A.
13.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
85
0
0
0
0
8
77
0
0
8
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
62
8
0
0
% C
% Asp:
0
0
0
0
8
0
8
0
0
0
8
8
0
62
16
% D
% Glu:
0
8
0
8
0
0
0
0
0
0
0
0
62
16
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% F
% Gly:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% G
% His:
8
0
77
0
0
0
0
0
8
8
8
0
0
0
8
% H
% Ile:
0
0
8
8
70
0
0
8
0
77
0
8
0
8
0
% I
% Lys:
0
0
0
0
8
8
0
8
0
0
0
8
8
0
62
% K
% Leu:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
85
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
8
% P
% Gln:
0
8
0
0
0
8
0
0
0
0
0
0
8
8
0
% Q
% Arg:
0
0
8
0
0
0
0
0
77
0
0
0
0
0
8
% R
% Ser:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% S
% Thr:
8
77
0
0
0
0
0
0
8
0
0
8
0
0
0
% T
% Val:
0
0
0
0
8
0
8
0
0
0
0
0
8
8
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
70
0
77
0
0
70
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _