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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZNF219 All Species: 11.21
Human Site: S598 Identified Species: 27.41
UniProt: Q9P2Y4 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P2Y4 NP_001095142.1 722 76877 S598 A S S P R P P S S G A G P G S
Chimpanzee Pan troglodytes XP_001148855 722 76833 S598 A S S P R P P S S G A G P G S
Rhesus Macaque Macaca mulatta XP_001095832 691 73553 S567 A S S P R P P S S G A G P G S
Dog Lupus familis XP_541723 1455 156931 R882 G L P G I D F R G G P A S Q Q
Cat Felis silvestris
Mouse Mus musculus Q8K083 1302 141558 R853 G L P G I D F R G G P A S Q Q
Rat Rattus norvegicus NP_001007682 726 77841 T601 G T A S T R P T S S S T G P G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507965 1380 150870 R853 G L P G I D F R G A P V S Q Q
Chicken Gallus gallus P30373 509 56690 S316 G K G F A W A S H L Q R H R R
Frog Xenopus laevis NP_001087732 593 66715 L484 N A D G S N E L E F R P P S R
Zebra Danio Brachydanio rerio XP_690204 959 103747 E663 S F G R V P G E A P S S R H T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 88 23.7 N.A. 26.4 88.2 N.A. 24.4 24.2 22.2 29.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.8 88.5 31.9 N.A. 35.4 90 N.A. 33.7 33.5 34.6 38.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 6.6 N.A. 6.6 13.3 N.A. 0 6.6 6.6 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 6.6 N.A. 6.6 40 N.A. 0 6.6 13.3 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 30 10 10 0 10 0 10 0 10 10 30 20 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 30 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 10 10 10 0 0 0 0 0 0 % E
% Phe: 0 10 0 10 0 0 30 0 0 10 0 0 0 0 0 % F
% Gly: 50 0 20 40 0 0 10 0 30 50 0 30 10 30 10 % G
% His: 0 0 0 0 0 0 0 0 10 0 0 0 10 10 0 % H
% Ile: 0 0 0 0 30 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 30 0 0 0 0 0 10 0 10 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 30 30 0 40 40 0 0 10 30 10 40 10 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 10 0 0 30 30 % Q
% Arg: 0 0 0 10 30 10 0 30 0 0 10 10 10 10 20 % R
% Ser: 10 30 30 10 10 0 0 40 40 10 20 10 30 10 30 % S
% Thr: 0 10 0 0 10 0 0 10 0 0 0 10 0 0 10 % T
% Val: 0 0 0 0 10 0 0 0 0 0 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _