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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZNF219
All Species:
30.91
Human Site:
Y543
Identified Species:
75.56
UniProt:
Q9P2Y4
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2Y4
NP_001095142.1
722
76877
Y543
T
Q
S
G
S
L
K
Y
H
L
Q
R
H
H
R
Chimpanzee
Pan troglodytes
XP_001148855
722
76833
Y543
T
Q
S
G
S
L
K
Y
H
L
Q
R
H
H
R
Rhesus Macaque
Macaca mulatta
XP_001095832
691
73553
Y512
T
Q
S
G
S
L
K
Y
H
L
Q
R
H
H
R
Dog
Lupus familis
XP_541723
1455
156931
Y827
T
Q
S
A
S
L
K
Y
H
L
E
R
H
H
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8K083
1302
141558
Y798
T
Q
S
A
S
L
K
Y
H
L
E
R
H
H
R
Rat
Rattus norvegicus
NP_001007682
726
77841
Y546
T
Q
S
G
S
L
K
Y
H
L
Q
R
H
H
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507965
1380
150870
Y798
T
Q
S
A
S
L
K
Y
H
L
E
R
H
H
R
Chicken
Gallus gallus
P30373
509
56690
H345
E
R
F
S
Q
K
A
H
L
L
Q
H
G
K
T
Frog
Xenopus laevis
NP_001087732
593
66715
D429
A
D
A
D
V
T
Y
D
N
G
K
E
E
Y
I
Zebra Danio
Brachydanio rerio
XP_690204
959
103747
Y608
T
Q
S
G
S
L
K
Y
H
L
Q
R
H
H
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
88
23.7
N.A.
26.4
88.2
N.A.
24.4
24.2
22.2
29.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
88.5
31.9
N.A.
35.4
90
N.A.
33.7
33.5
34.6
38.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
86.6
100
N.A.
86.6
13.3
0
100
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
100
N.A.
93.3
26.6
26.6
100
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
30
0
0
10
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
10
0
0
0
10
0
0
0
0
0
0
0
% D
% Glu:
10
0
0
0
0
0
0
0
0
0
30
10
10
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
50
0
0
0
0
0
10
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
10
80
0
0
10
80
80
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
0
10
80
0
0
0
10
0
0
10
0
% K
% Leu:
0
0
0
0
0
80
0
0
10
90
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
80
0
0
10
0
0
0
0
0
60
0
0
0
0
% Q
% Arg:
0
10
0
0
0
0
0
0
0
0
0
80
0
0
80
% R
% Ser:
0
0
80
10
80
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
80
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% T
% Val:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
80
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _