KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MBD2
All Species:
13.64
Human Site:
S168
Identified Species:
37.5
UniProt:
Q9UBB5
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBB5
NP_003918.1
411
43255
S168
K
E
E
V
I
R
K
S
G
L
S
A
G
K
S
Chimpanzee
Pan troglodytes
XP_512139
487
51829
S244
K
E
E
V
I
R
K
S
G
L
S
A
G
K
S
Rhesus Macaque
Macaca mulatta
XP_001082249
412
43316
S169
K
E
E
V
I
R
K
S
G
L
S
A
G
K
S
Dog
Lupus familis
XP_541093
341
38370
K115
L
S
S
S
P
S
G
K
K
F
R
S
K
P
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2E1
414
43524
S171
K
E
E
V
I
R
K
S
G
L
S
A
G
K
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507719
302
33422
R90
K
M
N
K
N
R
Q
R
M
R
Y
D
C
S
S
Chicken
Gallus gallus
NP_001012403
257
28512
K42
Y
Y
F
S
P
S
G
K
K
F
R
S
K
P
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792656
274
30760
R60
S
P
C
G
K
K
L
R
S
K
P
Q
L
A
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8VZT0
202
20964
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.7
99
64.4
N.A.
96.8
N.A.
N.A.
49.8
50.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
37.9
Protein Similarity:
100
83.7
99
67.4
N.A.
97.8
N.A.
N.A.
58.1
56.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
50.8
P-Site Identity:
100
100
100
0
N.A.
100
N.A.
N.A.
20
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
6.6
N.A.
100
N.A.
N.A.
26.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
27.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
45
0
12
0
% A
% Cys:
0
0
12
0
0
0
0
0
0
0
0
0
12
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% D
% Glu:
0
45
45
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
12
0
0
0
0
0
0
23
0
0
0
0
0
% F
% Gly:
0
0
0
12
0
0
23
0
45
0
0
0
45
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
45
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
56
0
0
12
12
12
45
23
23
12
0
0
23
45
0
% K
% Leu:
12
0
0
0
0
0
12
0
0
45
0
0
12
0
0
% L
% Met:
0
12
0
0
0
0
0
0
12
0
0
0
0
0
0
% M
% Asn:
0
0
12
0
12
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
12
0
0
23
0
0
0
0
0
12
0
0
23
0
% P
% Gln:
0
0
0
0
0
0
12
0
0
0
0
12
0
0
23
% Q
% Arg:
0
0
0
0
0
56
0
23
0
12
23
0
0
0
12
% R
% Ser:
12
12
12
23
0
23
0
45
12
0
45
23
0
12
56
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
45
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
12
12
0
0
0
0
0
0
0
0
12
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _