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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MBD2 All Species: 18.48
Human Site: S316 Identified Species: 50.83
UniProt: Q9UBB5 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UBB5 NP_003918.1 411 43255 S316 L Q G V G P G S N D E T L L S
Chimpanzee Pan troglodytes XP_512139 487 51829 S392 L Q G V G P G S N D E T L L S
Rhesus Macaque Macaca mulatta XP_001082249 412 43316 S317 L Q G V G P G S N D E T L L S
Dog Lupus familis XP_541093 341 38370 S246 L Q G V G P G S N D E T L L S
Cat Felis silvestris
Mouse Mus musculus Q9Z2E1 414 43524 S319 L Q G V G P G S N D E T L L S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507719 302 33422 S221 P G V W L N T S Q P L C K A F
Chicken Gallus gallus NP_001012403 257 28512 P173 L Q A L G P V P D D V T L L S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792656 274 30760 K191 S V G P G L T K D N L L Q S L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8VZT0 202 20964 V120 I K M M E G I V A T S Y S P G
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.7 99 64.4 N.A. 96.8 N.A. N.A. 49.8 50.8 N.A. N.A. N.A. N.A. N.A. N.A. 37.9
Protein Similarity: 100 83.7 99 67.4 N.A. 97.8 N.A. N.A. 58.1 56.4 N.A. N.A. N.A. N.A. N.A. N.A. 50.8
P-Site Identity: 100 100 100 100 N.A. 100 N.A. N.A. 6.6 60 N.A. N.A. N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 100 100 N.A. 100 N.A. N.A. 6.6 73.3 N.A. N.A. N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. 20.4 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 27.9 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 12 0 0 0 0 0 12 0 0 0 0 12 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 23 67 0 0 0 0 0 % D
% Glu: 0 0 0 0 12 0 0 0 0 0 56 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % F
% Gly: 0 12 67 0 78 12 56 0 0 0 0 0 0 0 12 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 12 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % I
% Lys: 0 12 0 0 0 0 0 12 0 0 0 0 12 0 0 % K
% Leu: 67 0 0 12 12 12 0 0 0 0 23 12 67 67 12 % L
% Met: 0 0 12 12 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 12 0 0 56 12 0 0 0 0 0 % N
% Pro: 12 0 0 12 0 67 0 12 0 12 0 0 0 12 0 % P
% Gln: 0 67 0 0 0 0 0 0 12 0 0 0 12 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 12 0 0 0 0 0 0 67 0 0 12 0 12 12 67 % S
% Thr: 0 0 0 0 0 0 23 0 0 12 0 67 0 0 0 % T
% Val: 0 12 12 56 0 0 12 12 0 0 12 0 0 0 0 % V
% Trp: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _