KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPS15L1
All Species:
23.03
Human Site:
S212
Identified Species:
42.22
UniProt:
Q9UBC2
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBC2
NP_067058.1
864
94255
S212
P
P
S
L
I
P
P
S
K
R
K
K
T
V
F
Chimpanzee
Pan troglodytes
XP_001139238
933
102460
M203
L
E
K
E
P
V
P
M
S
L
P
P
A
L
V
Rhesus Macaque
Macaca mulatta
XP_001113811
1015
110551
S317
P
P
S
L
I
P
P
S
K
R
K
K
T
V
F
Dog
Lupus familis
XP_541965
908
99427
S212
P
P
S
L
I
P
P
S
K
R
K
K
T
V
F
Cat
Felis silvestris
Mouse
Mus musculus
Q60902
907
99276
S212
P
P
P
L
I
P
P
S
K
R
K
K
T
V
F
Rat
Rattus norvegicus
NP_001025092
878
96428
S212
P
P
P
L
I
P
P
S
K
R
K
K
T
V
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418263
887
97653
K235
P
S
L
I
P
P
S
K
R
K
K
T
P
V
F
Frog
Xenopus laevis
O42287
1270
143652
S306
P
P
E
Y
I
P
P
S
F
R
R
V
R
S
G
Zebra Danio
Brachydanio rerio
XP_696575
951
104620
K241
L
I
P
P
S
K
R
K
K
S
S
G
S
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_726481
1106
119588
G218
P
P
E
L
R
K
P
G
G
A
G
P
P
P
K
Honey Bee
Apis mellifera
XP_001122937
1043
116535
L203
P
S
V
L
P
P
E
L
M
P
P
G
K
R
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192039
1179
125310
S300
P
N
K
L
I
P
P
S
K
R
K
K
P
A
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SAT8
1533
164753
F358
P
A
S
N
A
P
S
F
A
T
Q
Q
N
T
A
Conservation
Percent
Protein Identity:
100
44.2
83.9
90.5
N.A.
87.6
88.5
N.A.
N.A.
82
21.1
61.6
N.A.
31.2
34.1
N.A.
32.6
Protein Similarity:
100
61.5
84.1
92.1
N.A.
91.1
91.3
N.A.
N.A.
90.1
36.2
72.9
N.A.
46.4
49.9
N.A.
46.3
P-Site Identity:
100
6.6
100
100
N.A.
93.3
93.3
N.A.
N.A.
33.3
46.6
6.6
N.A.
26.6
20
N.A.
66.6
P-Site Similarity:
100
13.3
100
100
N.A.
93.3
93.3
N.A.
N.A.
53.3
53.3
20
N.A.
26.6
20
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
32.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
0
0
0
8
8
0
0
8
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
8
16
8
0
0
8
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
47
% F
% Gly:
0
0
0
0
0
0
0
8
8
0
8
16
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
8
54
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
16
0
0
16
0
16
54
8
54
47
8
0
16
% K
% Leu:
16
0
8
62
0
0
0
8
0
8
0
0
0
16
8
% L
% Met:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% M
% Asn:
0
8
0
8
0
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
85
54
24
8
24
77
70
0
0
8
16
16
24
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% Q
% Arg:
0
0
0
0
8
0
8
0
8
54
8
0
8
8
0
% R
% Ser:
0
16
31
0
8
0
16
54
8
8
8
0
8
8
8
% S
% Thr:
0
0
0
0
0
0
0
0
0
8
0
8
39
8
0
% T
% Val:
0
0
8
0
0
8
0
0
0
0
0
8
0
47
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _