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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EPS15L1 All Species: 23.64
Human Site: S229 Identified Species: 43.33
UniProt: Q9UBC2 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UBC2 NP_067058.1 864 94255 S229 A V P V L P A S P P P K D S L
Chimpanzee Pan troglodytes XP_001139238 933 102460 I220 S K R K T V S I S G S V R L I
Rhesus Macaque Macaca mulatta XP_001113811 1015 110551 S334 A V P V L P A S P P P K D S L
Dog Lupus familis XP_541965 908 99427 S229 A V P V L P A S P P P K D S L
Cat Felis silvestris
Mouse Mus musculus Q60902 907 99276 S229 A V P V L P A S P P P K D S L
Rat Rattus norvegicus NP_001025092 878 96428 S229 A V P V L P A S P P P K D S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_418263 887 97653 S252 A V P V L P A S P P P K D S L
Frog Xenopus laevis O42287 1270 143652 S323 L S I M S S V S V D Q R L P E
Zebra Danio Brachydanio rerio XP_696575 951 104620 P258 V P V L P G S P P P P K D S L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_726481 1106 119588 A235 M P P P P A G A A M P R A P S
Honey Bee Apis mellifera XP_001122937 1043 116535 P220 T A P I S K S P A P M S V I T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001192039 1179 125310 L317 S V S V L P G L P S A G A L R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7SAT8 1533 164753 P375 P T I Q Q P Q P Q P S N S A I
Conservation
Percent
Protein Identity: 100 44.2 83.9 90.5 N.A. 87.6 88.5 N.A. N.A. 82 21.1 61.6 N.A. 31.2 34.1 N.A. 32.6
Protein Similarity: 100 61.5 84.1 92.1 N.A. 91.1 91.3 N.A. N.A. 90.1 36.2 72.9 N.A. 46.4 49.9 N.A. 46.3
P-Site Identity: 100 0 100 100 N.A. 100 100 N.A. N.A. 100 6.6 46.6 N.A. 13.3 13.3 N.A. 33.3
P-Site Similarity: 100 20 100 100 N.A. 100 100 N.A. N.A. 100 20 60 N.A. 26.6 26.6 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 20.5
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 32.4
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 47 8 0 0 0 8 47 8 16 0 8 0 16 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 8 0 0 54 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 8 16 0 0 8 0 8 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 16 8 0 0 0 8 0 0 0 0 0 8 16 % I
% Lys: 0 8 0 8 0 8 0 0 0 0 0 54 0 0 0 % K
% Leu: 8 0 0 8 54 0 0 8 0 0 0 0 8 16 54 % L
% Met: 8 0 0 8 0 0 0 0 0 8 8 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % N
% Pro: 8 16 62 8 16 62 0 24 62 70 62 0 0 16 0 % P
% Gln: 0 0 0 8 8 0 8 0 8 0 8 0 0 0 0 % Q
% Arg: 0 0 8 0 0 0 0 0 0 0 0 16 8 0 8 % R
% Ser: 16 8 8 0 16 8 24 54 8 8 16 8 8 54 8 % S
% Thr: 8 8 0 0 8 0 0 0 0 0 0 0 0 0 8 % T
% Val: 8 54 8 54 0 8 8 0 8 0 0 8 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _