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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPS15L1
All Species:
28.18
Human Site:
S434
Identified Species:
51.67
UniProt:
Q9UBC2
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBC2
NP_067058.1
864
94255
S434
D
L
D
R
E
T
S
S
L
Q
E
L
E
A
Q
Chimpanzee
Pan troglodytes
XP_001139238
933
102460
N420
E
V
Q
R
E
N
T
N
L
Q
K
L
Q
A
Q
Rhesus Macaque
Macaca mulatta
XP_001113811
1015
110551
S539
D
L
D
R
E
T
S
S
L
Q
E
L
E
A
Q
Dog
Lupus familis
XP_541965
908
99427
S432
D
L
D
R
E
T
S
S
L
Q
E
L
E
A
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q60902
907
99276
S432
D
L
D
R
E
T
S
S
L
Q
E
L
E
A
Q
Rat
Rattus norvegicus
NP_001025092
878
96428
S434
D
L
D
R
E
T
S
S
L
Q
E
L
E
A
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418263
887
97653
N457
D
L
D
R
E
T
S
N
L
Q
E
L
E
A
Q
Frog
Xenopus laevis
O42287
1270
143652
S545
K
M
I
P
E
K
Q
S
L
I
D
Q
L
K
Q
Zebra Danio
Brachydanio rerio
XP_696575
951
104620
S495
D
L
D
R
E
T
S
S
L
Q
E
L
E
A
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_726481
1106
119588
T472
E
L
D
T
L
T
A
T
L
K
Q
L
E
N
Q
Honey Bee
Apis mellifera
XP_001122937
1043
116535
R433
Q
K
G
E
A
Q
K
R
L
N
D
L
K
A
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192039
1179
125310
Q181
E
L
D
K
S
S
A
Q
V
K
Q
L
E
N
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SAT8
1533
164753
A790
Q
V
R
K
T
E
K
A
I
A
D
A
R
L
E
Conservation
Percent
Protein Identity:
100
44.2
83.9
90.5
N.A.
87.6
88.5
N.A.
N.A.
82
21.1
61.6
N.A.
31.2
34.1
N.A.
32.6
Protein Similarity:
100
61.5
84.1
92.1
N.A.
91.1
91.3
N.A.
N.A.
90.1
36.2
72.9
N.A.
46.4
49.9
N.A.
46.3
P-Site Identity:
100
46.6
100
100
N.A.
100
100
N.A.
N.A.
93.3
26.6
100
N.A.
46.6
26.6
N.A.
33.3
P-Site Similarity:
100
86.6
100
100
N.A.
100
100
N.A.
N.A.
100
40
100
N.A.
80
40
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
32.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
16
8
0
8
0
8
0
70
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
54
0
70
0
0
0
0
0
0
0
24
0
0
0
0
% D
% Glu:
24
0
0
8
70
8
0
0
0
0
54
0
70
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
8
8
0
0
0
0
0
% I
% Lys:
8
8
0
16
0
8
16
0
0
16
8
0
8
8
0
% K
% Leu:
0
70
0
0
8
0
0
0
85
0
0
85
8
8
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
16
0
8
0
0
0
16
0
% N
% Pro:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
16
0
8
0
0
8
8
8
0
62
16
8
8
0
93
% Q
% Arg:
0
0
8
62
0
0
0
8
0
0
0
0
8
0
0
% R
% Ser:
0
0
0
0
8
8
54
54
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
8
8
62
8
8
0
0
0
0
0
0
0
% T
% Val:
0
16
0
0
0
0
0
0
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _