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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPS15L1
All Species:
23.33
Human Site:
S745
Identified Species:
42.78
UniProt:
Q9UBC2
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBC2
NP_067058.1
864
94255
S745
A
E
G
F
A
D
F
S
Q
M
S
K
P
P
P
Chimpanzee
Pan troglodytes
XP_001139238
933
102460
S765
G
G
G
F
A
D
F
S
T
L
S
K
V
N
N
Rhesus Macaque
Macaca mulatta
XP_001113811
1015
110551
S850
A
E
G
F
A
D
F
S
Q
M
S
K
P
P
P
Dog
Lupus familis
XP_541965
908
99427
S743
T
E
G
F
A
D
F
S
Q
M
A
K
P
P
T
Cat
Felis silvestris
Mouse
Mus musculus
Q60902
907
99276
S743
A
E
G
F
A
D
F
S
Q
M
S
K
P
P
P
Rat
Rattus norvegicus
NP_001025092
878
96428
D744
D
P
F
K
S
K
Q
D
T
P
A
L
P
P
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418263
887
97653
S768
S
E
G
F
A
D
F
S
Q
M
S
K
S
V
A
Frog
Xenopus laevis
O42287
1270
143652
S875
A
G
Q
H
R
Q
R
S
A
F
T
P
A
T
V
Zebra Danio
Brachydanio rerio
XP_696575
951
104620
S800
N
S
G
F
A
D
F
S
Q
M
S
K
G
F
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_726481
1106
119588
Q794
D
D
F
D
N
K
N
Q
R
T
A
D
V
K
L
Honey Bee
Apis mellifera
XP_001122937
1043
116535
A734
S
T
G
F
A
D
F
A
N
F
D
S
K
V
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192039
1179
125310
P965
D
P
F
G
S
I
D
P
F
G
G
S
A
F
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SAT8
1533
164753
E1173
K
K
K
A
A
M
A
E
A
K
E
K
E
A
Q
Conservation
Percent
Protein Identity:
100
44.2
83.9
90.5
N.A.
87.6
88.5
N.A.
N.A.
82
21.1
61.6
N.A.
31.2
34.1
N.A.
32.6
Protein Similarity:
100
61.5
84.1
92.1
N.A.
91.1
91.3
N.A.
N.A.
90.1
36.2
72.9
N.A.
46.4
49.9
N.A.
46.3
P-Site Identity:
100
53.3
100
80
N.A.
100
13.3
N.A.
N.A.
73.3
13.3
66.6
N.A.
0
33.3
N.A.
0
P-Site Similarity:
100
60
100
86.6
N.A.
100
26.6
N.A.
N.A.
80
20
66.6
N.A.
20
46.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
32.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
31
0
0
8
70
0
8
8
16
0
24
0
16
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
24
8
0
8
0
62
8
8
0
0
8
8
0
0
0
% D
% Glu:
0
39
0
0
0
0
0
8
0
0
8
0
8
0
8
% E
% Phe:
0
0
24
62
0
0
62
0
8
16
0
0
0
16
0
% F
% Gly:
8
16
62
8
0
0
0
0
0
8
8
0
8
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
8
8
8
0
16
0
0
0
8
0
62
8
8
16
% K
% Leu:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
8
% L
% Met:
0
0
0
0
0
8
0
0
0
47
0
0
0
0
0
% M
% Asn:
8
0
0
0
8
0
8
0
8
0
0
0
0
8
8
% N
% Pro:
0
16
0
0
0
0
0
8
0
8
0
8
39
39
24
% P
% Gln:
0
0
8
0
0
8
8
8
47
0
0
0
0
0
8
% Q
% Arg:
0
0
0
0
8
0
8
0
8
0
0
0
0
0
0
% R
% Ser:
16
8
0
0
16
0
0
62
0
0
47
16
8
0
0
% S
% Thr:
8
8
0
0
0
0
0
0
16
8
8
0
0
8
8
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
16
16
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _