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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EPS15L1 All Species: 30
Human Site: T239 Identified Species: 55
UniProt: Q9UBC2 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UBC2 NP_067058.1 864 94255 T239 P K D S L R S T P S H G S V S
Chimpanzee Pan troglodytes XP_001139238 933 102460 S230 S V R L I P S S A S A K E S Y
Rhesus Macaque Macaca mulatta XP_001113811 1015 110551 T344 P K D S L R S T P S H G S V S
Dog Lupus familis XP_541965 908 99427 T239 P K D S L R S T P S H G S V S
Cat Felis silvestris
Mouse Mus musculus Q60902 907 99276 T239 P K D S L R S T P S H G S V S
Rat Rattus norvegicus NP_001025092 878 96428 T239 P K D S L R S T P S H G S V S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_418263 887 97653 T262 P K D S L R S T P S H G S V N
Frog Xenopus laevis O42287 1270 143652 E333 Q R L P E E P E E E E P Q N A
Zebra Danio Brachydanio rerio XP_696575 951 104620 T268 P K D S L R S T P S H G S M N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_726481 1106 119588 G245 P R A P S G E G F G D G G F V
Honey Bee Apis mellifera XP_001122937 1043 116535 P230 M S V I T T V P P P I P P L P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001192039 1179 125310 T327 A G A L R R V T P P P T S P A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7SAT8 1533 164753 A385 S N S A I L Q A Q M T G F P A
Conservation
Percent
Protein Identity: 100 44.2 83.9 90.5 N.A. 87.6 88.5 N.A. N.A. 82 21.1 61.6 N.A. 31.2 34.1 N.A. 32.6
Protein Similarity: 100 61.5 84.1 92.1 N.A. 91.1 91.3 N.A. N.A. 90.1 36.2 72.9 N.A. 46.4 49.9 N.A. 46.3
P-Site Identity: 100 13.3 100 100 N.A. 100 100 N.A. N.A. 93.3 0 86.6 N.A. 13.3 6.6 N.A. 26.6
P-Site Similarity: 100 26.6 100 100 N.A. 100 100 N.A. N.A. 100 13.3 100 N.A. 20 13.3 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 20.5
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 32.4
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 16 8 0 0 0 8 8 0 8 0 0 0 24 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 54 0 0 0 0 0 0 0 8 0 0 0 0 % D
% Glu: 0 0 0 0 8 8 8 8 8 8 8 0 8 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 8 0 0 0 8 8 0 % F
% Gly: 0 8 0 0 0 8 0 8 0 8 0 70 8 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 54 0 0 0 0 % H
% Ile: 0 0 0 8 16 0 0 0 0 0 8 0 0 0 0 % I
% Lys: 0 54 0 0 0 0 0 0 0 0 0 8 0 0 0 % K
% Leu: 0 0 8 16 54 8 0 0 0 0 0 0 0 8 0 % L
% Met: 8 0 0 0 0 0 0 0 0 8 0 0 0 8 0 % M
% Asn: 0 8 0 0 0 0 0 0 0 0 0 0 0 8 16 % N
% Pro: 62 0 0 16 0 8 8 8 70 16 8 16 8 16 8 % P
% Gln: 8 0 0 0 0 0 8 0 8 0 0 0 8 0 0 % Q
% Arg: 0 16 8 0 8 62 0 0 0 0 0 0 0 0 0 % R
% Ser: 16 8 8 54 8 0 62 8 0 62 0 0 62 8 39 % S
% Thr: 0 0 0 0 8 8 0 62 0 0 8 8 0 0 0 % T
% Val: 0 8 8 0 0 0 16 0 0 0 0 0 0 47 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _