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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPS15L1
All Species:
20.61
Human Site:
T577
Identified Species:
37.78
UniProt:
Q9UBC2
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBC2
NP_067058.1
864
94255
T577
G
A
H
G
A
S
L
T
D
L
A
N
L
S
E
Chimpanzee
Pan troglodytes
XP_001139238
933
102460
Y563
L
V
N
G
A
T
D
Y
C
S
L
S
T
S
S
Rhesus Macaque
Macaca mulatta
XP_001113811
1015
110551
T682
G
A
H
G
A
S
L
T
D
L
A
D
L
S
E
Dog
Lupus familis
XP_541965
908
99427
T575
G
A
H
G
A
S
L
T
N
L
A
D
L
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q60902
907
99276
P575
G
V
S
G
T
S
L
P
D
L
A
T
L
N
E
Rat
Rattus norvegicus
NP_001025092
878
96428
F577
F
K
N
K
A
L
L
F
S
N
N
S
Q
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418263
887
97653
T600
G
V
N
G
G
S
L
T
N
L
A
D
I
S
E
Frog
Xenopus laevis
O42287
1270
143652
E677
K
F
Q
D
E
E
K
E
K
R
E
E
S
V
Q
Zebra Danio
Brachydanio rerio
XP_696575
951
104620
T638
G
T
H
G
G
S
M
T
N
L
A
D
M
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_726481
1106
119588
R608
E
P
D
F
D
E
A
R
K
T
L
T
K
E
V
Honey Bee
Apis mellifera
XP_001122937
1043
116535
P565
A
G
D
A
T
L
V
P
D
T
N
G
F
E
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192039
1179
125310
M675
T
A
N
S
T
G
T
M
P
Q
I
D
E
F
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SAT8
1533
164753
T993
G
S
Y
S
S
Y
K
T
P
E
E
R
A
A
F
Conservation
Percent
Protein Identity:
100
44.2
83.9
90.5
N.A.
87.6
88.5
N.A.
N.A.
82
21.1
61.6
N.A.
31.2
34.1
N.A.
32.6
Protein Similarity:
100
61.5
84.1
92.1
N.A.
91.1
91.3
N.A.
N.A.
90.1
36.2
72.9
N.A.
46.4
49.9
N.A.
46.3
P-Site Identity:
100
20
93.3
86.6
N.A.
60
13.3
N.A.
N.A.
60
0
60
N.A.
0
6.6
N.A.
6.6
P-Site Similarity:
100
40
100
100
N.A.
66.6
26.6
N.A.
N.A.
86.6
6.6
86.6
N.A.
0
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
32.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
31
0
8
39
0
8
0
0
0
47
0
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
0
16
8
8
0
8
0
31
0
0
39
0
0
0
% D
% Glu:
8
0
0
0
8
16
0
8
0
8
16
8
8
24
47
% E
% Phe:
8
8
0
8
0
0
0
8
0
0
0
0
8
8
8
% F
% Gly:
54
8
0
54
16
8
0
0
0
0
0
8
0
0
8
% G
% His:
0
0
31
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
0
% I
% Lys:
8
8
0
8
0
0
16
0
16
0
0
0
8
0
0
% K
% Leu:
8
0
0
0
0
16
47
0
0
47
16
0
31
0
8
% L
% Met:
0
0
0
0
0
0
8
8
0
0
0
0
8
0
0
% M
% Asn:
0
0
31
0
0
0
0
0
24
8
16
8
0
8
0
% N
% Pro:
0
8
0
0
0
0
0
16
16
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
0
0
0
0
8
0
0
8
0
16
% Q
% Arg:
0
0
0
0
0
0
0
8
0
8
0
8
0
0
0
% R
% Ser:
0
8
8
16
8
47
0
0
8
8
0
16
8
47
8
% S
% Thr:
8
8
0
0
24
8
8
47
0
16
0
16
8
0
0
% T
% Val:
0
24
0
0
0
0
8
0
0
0
0
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
8
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _