KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPS15L1
All Species:
10
Human Site:
T653
Identified Species:
18.33
UniProt:
Q9UBC2
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBC2
NP_067058.1
864
94255
T653
P
F
A
E
Q
Q
T
T
S
T
D
P
F
G
G
Chimpanzee
Pan troglodytes
XP_001139238
933
102460
F673
D
P
F
K
D
D
P
F
G
K
I
D
P
F
G
Rhesus Macaque
Macaca mulatta
XP_001113811
1015
110551
T758
P
F
A
E
Q
Q
T
T
S
T
D
P
F
G
G
Dog
Lupus familis
XP_541965
908
99427
A651
P
F
A
E
Q
Q
T
A
S
A
D
P
F
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q60902
907
99276
A651
P
F
S
E
Q
Q
T
A
A
T
D
P
F
G
G
Rat
Rattus norvegicus
NP_001025092
878
96428
K652
D
F
F
K
K
Q
T
K
N
D
P
F
T
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418263
887
97653
A676
P
F
A
E
Q
P
P
A
P
A
D
P
F
G
G
Frog
Xenopus laevis
O42287
1270
143652
F783
L
K
G
K
T
G
W
F
P
A
N
Y
A
E
R
Zebra Danio
Brachydanio rerio
XP_696575
951
104620
T708
P
F
S
K
P
A
T
T
V
P
D
P
F
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_726481
1106
119588
N702
A
F
A
A
N
K
S
N
A
I
T
P
E
P
G
Honey Bee
Apis mellifera
XP_001122937
1043
116535
P642
T
T
A
T
T
K
D
P
F
G
D
D
P
F
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192039
1179
125310
T873
F
A
P
K
G
S
T
T
D
S
D
P
F
A
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SAT8
1533
164753
P1081
P
K
A
D
S
R
P
P
P
P
P
P
S
R
K
Conservation
Percent
Protein Identity:
100
44.2
83.9
90.5
N.A.
87.6
88.5
N.A.
N.A.
82
21.1
61.6
N.A.
31.2
34.1
N.A.
32.6
Protein Similarity:
100
61.5
84.1
92.1
N.A.
91.1
91.3
N.A.
N.A.
90.1
36.2
72.9
N.A.
46.4
49.9
N.A.
46.3
P-Site Identity:
100
6.6
100
86.6
N.A.
80
20
N.A.
N.A.
66.6
0
60
N.A.
26.6
13.3
N.A.
33.3
P-Site Similarity:
100
13.3
100
86.6
N.A.
93.3
40
N.A.
N.A.
66.6
13.3
73.3
N.A.
46.6
20
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
32.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
54
8
0
8
0
24
16
24
0
0
8
8
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
0
0
8
8
8
8
0
8
8
62
16
0
0
8
% D
% Glu:
0
0
0
39
0
0
0
0
0
0
0
0
8
8
0
% E
% Phe:
8
62
16
0
0
0
0
16
8
0
0
8
54
16
0
% F
% Gly:
0
0
8
0
8
8
0
0
8
8
0
0
0
47
62
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% I
% Lys:
0
16
0
39
8
16
0
8
0
8
0
0
0
0
8
% K
% Leu:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
8
8
0
8
0
0
0
0
% N
% Pro:
54
8
8
0
8
8
24
16
24
16
16
70
16
8
0
% P
% Gln:
0
0
0
0
39
39
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
8
% R
% Ser:
0
0
16
0
8
8
8
0
24
8
0
0
8
8
0
% S
% Thr:
8
8
0
8
16
0
54
31
0
24
8
0
8
0
0
% T
% Val:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _