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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPS15L1
All Species:
31.21
Human Site:
Y19
Identified Species:
57.22
UniProt:
Q9UBC2
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBC2
NP_067058.1
864
94255
Y19
I
P
T
G
N
S
L
Y
E
S
Y
Y
K
Q
V
Chimpanzee
Pan troglodytes
XP_001139238
933
102460
Y19
L
S
S
G
N
S
V
Y
E
K
Y
Y
R
Q
V
Rhesus Macaque
Macaca mulatta
XP_001113811
1015
110551
Y124
I
P
T
G
N
S
L
Y
E
S
Y
Y
K
Q
V
Dog
Lupus familis
XP_541965
908
99427
Y19
I
P
T
G
N
P
L
Y
E
S
Y
Y
K
Q
V
Cat
Felis silvestris
Mouse
Mus musculus
Q60902
907
99276
Y19
I
P
S
G
N
P
L
Y
E
S
Y
Y
K
Q
V
Rat
Rattus norvegicus
NP_001025092
878
96428
Y19
I
P
S
G
N
P
L
Y
E
S
Y
Y
K
Q
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418263
887
97653
Y41
F
S
A
G
I
P
L
Y
E
T
Y
Y
K
Q
V
Frog
Xenopus laevis
O42287
1270
143652
N69
W
A
L
A
D
M
N
N
D
G
R
M
D
Q
L
Zebra Danio
Brachydanio rerio
XP_696575
951
104620
Y44
L
S
S
G
N
P
V
Y
E
N
F
Y
R
Q
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_726481
1106
119588
K26
Y
Y
K
L
I
D
P
K
G
T
G
A
I
E
A
Honey Bee
Apis mellifera
XP_001122937
1043
116535
Y18
A
G
S
H
T
A
I
Y
E
A
Y
Y
N
Q
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192039
1179
125310
C19
T
S
E
D
S
A
N
C
Y
I
L
F
K
Q
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SAT8
1533
164753
Q105
Q
F
T
G
F
Q
P
Q
A
T
G
F
Q
P
Q
Conservation
Percent
Protein Identity:
100
44.2
83.9
90.5
N.A.
87.6
88.5
N.A.
N.A.
82
21.1
61.6
N.A.
31.2
34.1
N.A.
32.6
Protein Similarity:
100
61.5
84.1
92.1
N.A.
91.1
91.3
N.A.
N.A.
90.1
36.2
72.9
N.A.
46.4
49.9
N.A.
46.3
P-Site Identity:
100
60
100
93.3
N.A.
86.6
86.6
N.A.
N.A.
60
6.6
46.6
N.A.
0
40
N.A.
13.3
P-Site Similarity:
100
86.6
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
66.6
26.6
86.6
N.A.
13.3
66.6
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
32.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
8
0
16
0
0
8
8
0
8
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
8
8
0
0
8
0
0
0
8
0
0
% D
% Glu:
0
0
8
0
0
0
0
0
70
0
0
0
0
8
0
% E
% Phe:
8
8
0
0
8
0
0
0
0
0
8
16
0
0
0
% F
% Gly:
0
8
0
70
0
0
0
0
8
8
16
0
0
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
39
0
0
0
16
0
8
0
0
8
0
0
8
0
0
% I
% Lys:
0
0
8
0
0
0
0
8
0
8
0
0
54
0
0
% K
% Leu:
16
0
8
8
0
0
47
0
0
0
8
0
0
0
16
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
54
0
16
8
0
8
0
0
8
0
0
% N
% Pro:
0
39
0
0
0
39
16
0
0
0
0
0
0
8
0
% P
% Gln:
8
0
0
0
0
8
0
8
0
0
0
0
8
85
8
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
8
0
16
0
0
% R
% Ser:
0
31
39
0
8
24
0
0
0
39
0
0
0
0
0
% S
% Thr:
8
0
31
0
8
0
0
0
0
24
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
16
0
0
0
0
0
0
0
70
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
0
0
0
0
70
8
0
62
70
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _