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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PI4KB All Species: 28.48
Human Site: S124 Identified Species: 56.97
UniProt: Q9UBF8 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UBF8 NP_002642.1 816 91379 S124 R R R R Q N N S A K Q S W L L
Chimpanzee Pan troglodytes XP_001171600 816 91257 S124 R R R R Q N N S A K Q S W L L
Rhesus Macaque Macaca mulatta XP_001106422 828 92728 S136 R R R R Q N N S A K Q S W L L
Dog Lupus familis XP_540314 945 105487 S253 R R R R Q N N S A K Q S W L L
Cat Felis silvestris
Mouse Mus musculus Q8BKC8 816 91497 S124 R R R R Q N N S A K Q S W L L
Rat Rattus norvegicus O08561 816 91637 S124 R R R R Q N N S A K Q S W L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_423394 743 82507 R98 L V E G C E I R C L D D L P G
Frog Xenopus laevis Q6GN16 804 90437 S109 S R I N E E E S P L D I N S V
Zebra Danio Brachydanio rerio Q49GP3 835 94040 S144 R R R Q K N N S S K Q S W L L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524822 1674 181956 E896 S D V L Q K P E K G Q S G L L
Honey Bee Apis mellifera XP_391922 1078 119863 K332 R Q E T V Q P K P S E G C L L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P39104 1066 119905 K151 S G S D K N V K I H E N V A P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 98.1 84.2 N.A. 98.5 97.6 N.A. N.A. 78.6 85.2 74.9 N.A. 25.7 42.1 N.A. N.A.
Protein Similarity: 100 99.2 98.3 84.9 N.A. 99.1 98.6 N.A. N.A. 83.4 90 82.7 N.A. 36.2 55.5 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 0 13.3 80 N.A. 33.3 20 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 0 26.6 100 N.A. 33.3 33.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 24.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 44 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 50 0 0 0 0 9 0 % A
% Cys: 0 0 0 0 9 0 0 0 9 0 0 0 9 0 0 % C
% Asp: 0 9 0 9 0 0 0 0 0 0 17 9 0 0 0 % D
% Glu: 0 0 17 0 9 17 9 9 0 0 17 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 9 0 9 0 0 0 0 0 9 0 9 9 0 9 % G
% His: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % H
% Ile: 0 0 9 0 0 0 9 0 9 0 0 9 0 0 0 % I
% Lys: 0 0 0 0 17 9 0 17 9 59 0 0 0 0 0 % K
% Leu: 9 0 0 9 0 0 0 0 0 17 0 0 9 75 75 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 9 0 67 59 0 0 0 0 9 9 0 0 % N
% Pro: 0 0 0 0 0 0 17 0 17 0 0 0 0 9 9 % P
% Gln: 0 9 0 9 59 9 0 0 0 0 67 0 0 0 0 % Q
% Arg: 67 67 59 50 0 0 0 9 0 0 0 0 0 0 0 % R
% Ser: 25 0 9 0 0 0 0 67 9 9 0 67 0 9 0 % S
% Thr: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 9 9 0 9 0 9 0 0 0 0 0 9 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 59 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _