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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PI4KB All Species: 25.45
Human Site: Y641 Identified Species: 50.91
UniProt: Q9UBF8 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UBF8 NP_002642.1 816 91379 Y641 F L Q E H G S Y T T E A F L S
Chimpanzee Pan troglodytes XP_001171600 816 91257 Y641 F L Q E H G S Y T T E A F L S
Rhesus Macaque Macaca mulatta XP_001106422 828 92728 Y653 F L Q E H G S Y T T E A F L S
Dog Lupus familis XP_540314 945 105487 Y770 F L Q E H G S Y T T E A F L S
Cat Felis silvestris
Mouse Mus musculus Q8BKC8 816 91497 Y641 F L Q E H G S Y T T E A F L S
Rat Rattus norvegicus O08561 816 91637 Y641 F L Q E H G S Y T T E A F L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_423394 743 82507 R599 Q S I W E Q E R V P L W I K P
Frog Xenopus laevis Q6GN16 804 90437 C629 F L Q E H G S C T T E A F L T
Zebra Danio Brachydanio rerio Q49GP3 835 94040 F660 F R Q E H G N F N T E E F L T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524822 1674 181956 P1497 F I D E Y G S P S G E S F R R
Honey Bee Apis mellifera XP_391922 1078 119863 S901 F E R E F G P S M S E A F I I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P39104 1066 119905 G873 A E L D D K G G I A S L N D H
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 98.1 84.2 N.A. 98.5 97.6 N.A. N.A. 78.6 85.2 74.9 N.A. 25.7 42.1 N.A. N.A.
Protein Similarity: 100 99.2 98.3 84.9 N.A. 99.1 98.6 N.A. N.A. 83.4 90 82.7 N.A. 36.2 55.5 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 0 86.6 60 N.A. 40 40 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 0 93.3 80 N.A. 66.6 60 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 24.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 44 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 0 0 0 0 0 9 0 67 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % C
% Asp: 0 0 9 9 9 0 0 0 0 0 0 0 0 9 0 % D
% Glu: 0 17 0 84 9 0 9 0 0 0 84 9 0 0 0 % E
% Phe: 84 0 0 0 9 0 0 9 0 0 0 0 84 0 0 % F
% Gly: 0 0 0 0 0 84 9 9 0 9 0 0 0 0 0 % G
% His: 0 0 0 0 67 0 0 0 0 0 0 0 0 0 9 % H
% Ile: 0 9 9 0 0 0 0 0 9 0 0 0 9 9 9 % I
% Lys: 0 0 0 0 0 9 0 0 0 0 0 0 0 9 0 % K
% Leu: 0 59 9 0 0 0 0 0 0 0 9 9 0 67 0 % L
% Met: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 9 0 9 0 0 0 9 0 0 % N
% Pro: 0 0 0 0 0 0 9 9 0 9 0 0 0 0 9 % P
% Gln: 9 0 67 0 0 9 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 9 9 0 0 0 0 9 0 0 0 0 0 9 9 % R
% Ser: 0 9 0 0 0 0 67 9 9 9 9 9 0 0 50 % S
% Thr: 0 0 0 0 0 0 0 0 59 67 0 0 0 0 17 % T
% Val: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % V
% Trp: 0 0 0 9 0 0 0 0 0 0 0 9 0 0 0 % W
% Tyr: 0 0 0 0 9 0 0 50 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _