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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: XPR1 All Species: 36.36
Human Site: S666 Identified Species: 66.67
UniProt: Q9UBH6 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UBH6 NP_001129141.1 696 81535 S666 R S W K Y N Q S I S L R R P R
Chimpanzee Pan troglodytes XP_001159014 665 77878 S635 R S W K Y N Q S I S L R R P R
Rhesus Macaque Macaca mulatta XP_001115004 696 81617 S666 R S W K Y N Q S I S L R R P R
Dog Lupus familis XP_547421 696 81447 S666 R P W K Y S Q S I S L R R P R
Cat Felis silvestris
Mouse Mus musculus Q9Z0U0 695 81733 S665 R S W K Y N Q S I S L R R P R
Rat Rattus norvegicus NP_001099462 696 81717 S666 R S W K Y N Q S I S L R R P R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515839 719 83541 S689 K S W K C N Q S L A L R R P R
Chicken Gallus gallus XP_422258 695 80997 S665 K Q W K R S Q S I S L R R P R
Frog Xenopus laevis Q6DD44 692 80920 S662 R I W K R S Q S M S L R R P R
Zebra Danio Brachydanio rerio A8DZH4 693 81263 S663 G K K N W K R S Y S M S L R R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_573265 674 78357 P642 R Y T K A N R P K P K K V K D
Honey Bee Apis mellifera XP_624183 668 77075 K636 N G V L N R G K R K V G G K R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P40528 902 104199 A872 I S R S I P W A H A T D F Q R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.6 97.9 98.1 N.A. 95.2 95.9 N.A. 83.4 83.7 84.6 79.8 N.A. 54.4 53.8 N.A. N.A.
Protein Similarity: 100 95.4 98.9 98.4 N.A. 97.4 97.6 N.A. 89.7 90.5 92 88 N.A. 69.5 69.8 N.A. N.A.
P-Site Identity: 100 100 100 86.6 N.A. 100 100 N.A. 73.3 73.3 73.3 20 N.A. 20 6.6 N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 100 100 N.A. 93.3 86.6 86.6 40 N.A. 33.3 13.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 38 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 0 0 8 0 16 0 0 0 0 0 % A
% Cys: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 8 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % F
% Gly: 8 8 0 0 0 0 8 0 0 0 0 8 8 0 0 % G
% His: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % H
% Ile: 8 8 0 0 8 0 0 0 54 0 0 0 0 0 0 % I
% Lys: 16 8 8 77 0 8 0 8 8 8 8 8 0 16 0 % K
% Leu: 0 0 0 8 0 0 0 0 8 0 70 0 8 0 0 % L
% Met: 0 0 0 0 0 0 0 0 8 0 8 0 0 0 0 % M
% Asn: 8 0 0 8 8 54 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 8 0 0 0 8 0 8 0 8 0 0 0 70 0 % P
% Gln: 0 8 0 0 0 0 70 0 0 0 0 0 0 8 0 % Q
% Arg: 62 0 8 0 16 8 16 0 8 0 0 70 70 8 93 % R
% Ser: 0 54 0 8 0 24 0 77 0 70 0 8 0 0 0 % S
% Thr: 0 0 8 0 0 0 0 0 0 0 8 0 0 0 0 % T
% Val: 0 0 8 0 0 0 0 0 0 0 8 0 8 0 0 % V
% Trp: 0 0 70 0 8 0 8 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 47 0 0 0 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _