KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HECA
All Species:
16.36
Human Site:
S205
Identified Species:
45
UniProt:
Q9UBI9
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBI9
NP_057301.1
543
58837
S205
Q
D
E
K
K
K
K
S
G
S
E
K
N
T
G
Chimpanzee
Pan troglodytes
XP_527517
543
58864
S205
Q
D
E
K
K
K
K
S
G
S
E
K
N
T
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533428
481
54144
P165
E
E
A
K
K
C
R
P
P
N
K
P
Q
K
G
Cat
Felis silvestris
Mouse
Mus musculus
NP_001028604
544
59098
S206
Q
D
E
K
K
K
K
S
G
S
E
K
N
T
A
Rat
Rattus norvegicus
NP_001100984
415
47301
P141
A
R
S
P
C
G
S
P
G
Q
S
P
P
T
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_419714
509
55782
S171
Q
D
D
K
K
K
K
S
V
L
E
K
S
T
G
Frog
Xenopus laevis
NP_001084967
492
54486
S185
Q
D
E
K
K
K
K
S
A
T
E
K
L
C
G
Zebra Danio
Brachydanio rerio
NP_001038591
523
58058
M167
Q
D
E
R
K
K
K
M
P
E
K
G
S
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780346
721
79358
N185
S
I
S
S
N
S
G
N
G
N
G
N
G
N
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
83
N.A.
95.4
74
N.A.
N.A.
85.4
63.7
73.4
N.A.
N.A.
N.A.
N.A.
24.6
Protein Similarity:
100
99.8
N.A.
84.7
N.A.
96.3
74.5
N.A.
N.A.
87.6
72
79.7
N.A.
N.A.
N.A.
N.A.
35
P-Site Identity:
100
100
N.A.
20
N.A.
93.3
20
N.A.
N.A.
73.3
73.3
40
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
N.A.
53.3
N.A.
93.3
20
N.A.
N.A.
86.6
80
60
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
12
0
0
0
0
0
12
0
0
0
0
0
12
% A
% Cys:
0
0
0
0
12
12
0
0
0
0
0
0
0
12
0
% C
% Asp:
0
67
12
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
12
12
56
0
0
0
0
0
0
12
56
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
12
12
0
56
0
12
12
12
12
78
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
67
78
67
67
0
0
0
23
56
0
12
12
% K
% Leu:
0
0
0
0
0
0
0
0
0
12
0
0
12
0
0
% L
% Met:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
12
0
0
12
0
23
0
12
34
12
0
% N
% Pro:
0
0
0
12
0
0
0
23
23
0
0
23
12
0
0
% P
% Gln:
67
0
0
0
0
0
0
0
0
12
0
0
12
0
0
% Q
% Arg:
0
12
0
12
0
0
12
0
0
0
0
0
0
0
0
% R
% Ser:
12
0
23
12
0
12
12
56
0
34
12
0
23
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
12
0
0
0
56
0
% T
% Val:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _