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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPARGC1A
All Species:
22.73
Human Site:
Y654
Identified Species:
83.33
UniProt:
Q9UBK2
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBK2
NP_037393.1
798
91027
Y654
R
E
E
Y
R
R
E
Y
E
K
R
E
S
E
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001105289
798
91073
Y654
R
E
E
Y
R
R
E
Y
E
K
R
E
S
E
R
Dog
Lupus familis
XP_851741
796
90531
Y652
R
E
E
Y
R
R
E
Y
E
K
R
E
S
E
R
Cat
Felis silvestris
Mouse
Mus musculus
O70343
797
90569
H653
R
D
E
Y
R
K
E
H
E
K
R
E
S
E
R
Rat
Rattus norvegicus
Q9QYK2
796
90603
Y652
R
D
E
Y
R
R
E
Y
E
K
R
E
S
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514399
795
90762
Y651
R
E
E
Y
R
K
E
Y
E
K
R
E
S
E
R
Chicken
Gallus gallus
NP_001006457
795
90514
Y651
R
E
E
Y
R
K
E
Y
E
K
R
E
S
E
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.2
96.7
N.A.
94.6
95.1
N.A.
88.8
88.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
99.5
97.8
N.A.
97.2
97.4
N.A.
92.8
93.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
80
93.3
N.A.
93.3
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
29
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
72
100
0
0
0
100
0
100
0
0
100
0
100
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
43
0
0
0
100
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
100
0
0
0
100
58
0
0
0
0
100
0
0
0
100
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
100
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
100
0
0
0
86
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _