Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MTRR All Species: 4.85
Human Site: S226 Identified Species: 8.21
UniProt: Q9UBK8 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.23
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UBK8 NP_002445.2 725 80410 S226 E L L R F D D S G R K D S E V
Chimpanzee Pan troglodytes XP_001145250 725 80375 S226 E L L R F D D S G G K D S E V
Rhesus Macaque Macaca mulatta XP_001109664 680 76966 L208 Q R I F E L G L G D D D G N L
Dog Lupus familis XP_535797 697 77934 P198 E L L R L D D P G R K D S E V
Cat Felis silvestris
Mouse Mus musculus P37040 678 77025 L205 Q R I F E L G L G D D D G N L
Rat Rattus norvegicus P00388 678 76944 G206 R I F E L G L G D D D G N L E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519075 915 101962 D420 I E L L R L D D S G V K R S P
Chicken Gallus gallus Q90703 1136 129631 G656 Q L T P V G E G D E L N G Q E
Frog Xenopus laevis Q6NRG5 600 68059 L163 M F P L R P G L E I I S E D V
Zebra Danio Brachydanio rerio Q6PFP6 595 66871 P158 Q K T L S L Y P P P A G L A P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q17574 682 76816 L208 R V I G I D M L I P E H Y D Y
Sea Urchin Strong. purpuratus XP_787027 728 80257 T262 T P S Q S T S T D P F I K V E
Poplar Tree Populus trichocarpa XP_002307336 692 76707 D218 V P V G L G D D D Q C I E D D
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_194183 692 76747 D218 L I E V G L G D D D Q S I E D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 27.3 80.6 N.A. 28.1 27.8 N.A. 56 21.2 28 28.5 N.A. N.A. N.A. 31.5 42.9
Protein Similarity: 100 99.1 44.8 87 N.A. 45 44.5 N.A. 65.4 35.9 46.2 44.5 N.A. N.A. N.A. 48.4 60.5
P-Site Identity: 100 93.3 13.3 86.6 N.A. 13.3 0 N.A. 13.3 6.6 6.6 0 N.A. N.A. N.A. 6.6 0
P-Site Similarity: 100 93.3 33.3 86.6 N.A. 33.3 13.3 N.A. 13.3 33.3 13.3 6.6 N.A. N.A. N.A. 33.3 13.3
Percent
Protein Identity: 28.1 N.A. N.A. 24.8 N.A. N.A.
Protein Similarity: 47 N.A. N.A. 44.1 N.A. N.A.
P-Site Identity: 6.6 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 26.6 N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 8 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % C
% Asp: 0 0 0 0 0 29 36 22 36 29 22 36 0 22 15 % D
% Glu: 22 8 8 8 15 0 8 0 8 8 8 0 15 29 22 % E
% Phe: 0 8 8 15 15 0 0 0 0 0 8 0 0 0 0 % F
% Gly: 0 0 0 15 8 22 29 15 36 15 0 15 22 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % H
% Ile: 8 15 22 0 8 0 0 0 8 8 8 15 8 0 0 % I
% Lys: 0 8 0 0 0 0 0 0 0 0 22 8 8 0 0 % K
% Leu: 8 29 29 22 22 36 8 29 0 0 8 0 8 8 15 % L
% Met: 8 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 8 8 15 0 % N
% Pro: 0 15 8 8 0 8 0 15 8 22 0 0 0 0 15 % P
% Gln: 29 0 0 8 0 0 0 0 0 8 8 0 0 8 0 % Q
% Arg: 15 15 0 22 15 0 0 0 0 15 0 0 8 0 0 % R
% Ser: 0 0 8 0 15 0 8 15 8 0 0 15 22 8 0 % S
% Thr: 8 0 15 0 0 8 0 8 0 0 0 0 0 0 0 % T
% Val: 8 8 8 8 8 0 0 0 0 0 8 0 0 8 29 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 0 0 0 0 0 8 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _