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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MTRR
All Species:
15.15
Human Site:
S258
Identified Species:
25.64
UniProt:
Q9UBK8
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBK8
NP_002445.2
725
80410
S258
F
E
S
S
L
T
R
S
V
P
P
L
S
Q
A
Chimpanzee
Pan troglodytes
XP_001145250
725
80375
S258
F
E
S
S
L
T
R
S
E
P
P
L
S
Q
A
Rhesus Macaque
Macaca mulatta
XP_001109664
680
76966
G240
H
F
G
V
E
A
T
G
E
E
S
S
I
R
Q
Dog
Lupus familis
XP_535797
697
77934
S230
S
Q
S
S
L
T
H
S
I
P
P
L
S
Q
A
Cat
Felis silvestris
Mouse
Mus musculus
P37040
678
77025
G237
F
F
G
V
E
A
T
G
E
E
S
S
I
R
Q
Rat
Rattus norvegicus
P00388
678
76944
E238
F
G
V
E
A
T
G
E
E
S
S
I
R
Q
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519075
915
101962
S452
L
E
S
S
L
I
R
S
V
P
P
L
S
R
A
Chicken
Gallus gallus
Q90703
1136
129631
S688
F
D
I
R
G
K
N
S
I
Q
L
P
E
I
Y
Frog
Xenopus laevis
Q6NRG5
600
68059
Y195
S
E
L
S
G
D
A
Y
E
R
D
F
I
S
N
Zebra Danio
Brachydanio rerio
Q6PFP6
595
66871
E190
E
V
P
N
K
L
T
E
H
L
Q
T
V
D
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17574
682
76816
Q240
L
R
V
P
I
A
P
Q
P
F
I
V
S
S
V
Sea Urchin
Strong. purpuratus
XP_787027
728
80257
S294
S
L
P
P
L
S
E
S
G
L
T
L
P
A
L
Poplar Tree
Populus trichocarpa
XP_002307336
692
76707
P250
D
E
D
D
V
N
A
P
S
T
P
Y
T
A
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_194183
692
76747
V250
K
D
E
D
D
K
S
V
A
T
P
Y
T
A
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
27.3
80.6
N.A.
28.1
27.8
N.A.
56
21.2
28
28.5
N.A.
N.A.
N.A.
31.5
42.9
Protein Similarity:
100
99.1
44.8
87
N.A.
45
44.5
N.A.
65.4
35.9
46.2
44.5
N.A.
N.A.
N.A.
48.4
60.5
P-Site Identity:
100
93.3
0
73.3
N.A.
6.6
20
N.A.
80
13.3
13.3
0
N.A.
N.A.
N.A.
6.6
20
P-Site Similarity:
100
93.3
6.6
86.6
N.A.
13.3
26.6
N.A.
86.6
26.6
13.3
6.6
N.A.
N.A.
N.A.
20
26.6
Percent
Protein Identity:
28.1
N.A.
N.A.
24.8
N.A.
N.A.
Protein Similarity:
47
N.A.
N.A.
44.1
N.A.
N.A.
P-Site Identity:
20
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
22
15
0
8
0
0
0
0
22
36
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
15
8
15
8
8
0
0
0
0
8
0
0
8
0
% D
% Glu:
8
36
8
8
15
0
8
15
36
15
0
0
8
0
0
% E
% Phe:
36
15
0
0
0
0
0
0
0
8
0
8
0
0
0
% F
% Gly:
0
8
15
0
15
0
8
15
8
0
0
0
0
0
0
% G
% His:
8
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
8
8
0
0
15
0
8
8
22
8
0
% I
% Lys:
8
0
0
0
8
15
0
0
0
0
0
0
0
0
0
% K
% Leu:
15
8
8
0
36
8
0
0
0
15
8
36
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
8
8
0
0
0
0
0
0
0
15
% N
% Pro:
0
0
15
15
0
0
8
8
8
29
43
8
8
0
0
% P
% Gln:
0
8
0
0
0
0
0
8
0
8
8
0
0
29
15
% Q
% Arg:
0
8
0
8
0
0
22
0
0
8
0
0
8
22
0
% R
% Ser:
22
0
29
36
0
8
8
43
8
8
22
15
36
15
0
% S
% Thr:
0
0
0
0
0
29
22
0
0
15
8
8
15
0
0
% T
% Val:
0
8
15
15
8
0
0
8
15
0
0
8
8
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
15
0
0
15
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _