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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MTRR
All Species:
21.21
Human Site:
S333
Identified Species:
35.9
UniProt:
Q9UBK8
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBK8
NP_002445.2
725
80410
S333
D
I
S
N
T
D
F
S
Y
Q
P
G
D
A
F
Chimpanzee
Pan troglodytes
XP_001145250
725
80375
S333
D
I
S
N
T
D
F
S
Y
Q
P
G
D
A
F
Rhesus Macaque
Macaca mulatta
XP_001109664
680
76966
I315
L
D
I
S
D
S
K
I
R
Y
E
S
G
D
H
Dog
Lupus familis
XP_535797
697
77934
S305
D
I
S
K
T
D
F
S
Y
Q
P
G
D
A
F
Cat
Felis silvestris
Mouse
Mus musculus
P37040
678
77025
I312
L
D
I
S
D
S
K
I
R
Y
E
S
G
D
H
Rat
Rattus norvegicus
P00388
678
76944
R313
D
I
S
D
S
K
I
R
Y
E
S
G
D
H
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519075
915
101962
S527
D
I
S
K
T
S
F
S
Y
Q
P
G
D
S
F
Chicken
Gallus gallus
Q90703
1136
129631
H763
C
E
T
N
Q
E
V
H
Y
L
P
G
E
H
I
Frog
Xenopus laevis
Q6NRG5
600
68059
L270
V
E
Q
F
C
S
L
L
H
L
D
P
L
N
K
Zebra Danio
Brachydanio rerio
Q6PFP6
595
66871
K265
E
Q
L
C
Q
L
L
K
L
D
P
E
S
Y
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17574
682
76816
D315
E
L
Q
Y
E
P
G
D
A
I
Y
F
C
V
P
Sea Urchin
Strong. purpuratus
XP_787027
728
80257
S369
K
V
A
E
N
S
M
S
F
Q
P
G
D
S
F
Poplar Tree
Populus trichocarpa
XP_002307336
692
76707
T325
D
I
T
G
T
G
I
T
Y
E
T
G
D
H
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_194183
692
76747
T325
D
I
S
R
T
G
I
T
Y
E
T
G
D
H
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
27.3
80.6
N.A.
28.1
27.8
N.A.
56
21.2
28
28.5
N.A.
N.A.
N.A.
31.5
42.9
Protein Similarity:
100
99.1
44.8
87
N.A.
45
44.5
N.A.
65.4
35.9
46.2
44.5
N.A.
N.A.
N.A.
48.4
60.5
P-Site Identity:
100
100
0
93.3
N.A.
0
40
N.A.
80
26.6
0
13.3
N.A.
N.A.
N.A.
0
40
P-Site Similarity:
100
100
6.6
93.3
N.A.
6.6
60
N.A.
86.6
46.6
6.6
20
N.A.
N.A.
N.A.
13.3
66.6
Percent
Protein Identity:
28.1
N.A.
N.A.
24.8
N.A.
N.A.
Protein Similarity:
47
N.A.
N.A.
44.1
N.A.
N.A.
P-Site Identity:
40
N.A.
N.A.
46.6
N.A.
N.A.
P-Site Similarity:
60
N.A.
N.A.
60
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
8
0
0
0
0
22
0
% A
% Cys:
8
0
0
8
8
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
50
15
0
8
15
22
0
8
0
8
8
0
58
15
0
% D
% Glu:
15
15
0
8
8
8
0
0
0
22
15
8
8
0
0
% E
% Phe:
0
0
0
8
0
0
29
0
8
0
0
8
0
0
43
% F
% Gly:
0
0
0
8
0
15
8
0
0
0
0
65
15
0
0
% G
% His:
0
0
0
0
0
0
0
8
8
0
0
0
0
29
15
% H
% Ile:
0
50
15
0
0
0
22
15
0
8
0
0
0
0
8
% I
% Lys:
8
0
0
15
0
8
15
8
0
0
0
0
0
0
8
% K
% Leu:
15
8
8
0
0
8
15
8
8
15
0
0
8
0
8
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
22
8
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
8
0
0
0
0
50
8
0
0
8
% P
% Gln:
0
8
15
0
15
0
0
0
0
36
0
0
0
0
0
% Q
% Arg:
0
0
0
8
0
0
0
8
15
0
0
0
0
0
0
% R
% Ser:
0
0
43
15
8
36
0
36
0
0
8
15
8
15
0
% S
% Thr:
0
0
15
0
43
0
0
15
0
0
15
0
0
0
0
% T
% Val:
8
8
0
0
0
0
8
0
0
0
0
0
0
8
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
58
15
8
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _