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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MTRR
All Species:
4.55
Human Site:
S422
Identified Species:
7.69
UniProt:
Q9UBK8
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBK8
NP_002445.2
725
80410
S422
L
V
D
Y
T
S
D
S
A
E
K
R
R
L
Q
Chimpanzee
Pan troglodytes
XP_001145250
725
80375
S422
L
V
D
Y
T
S
D
S
A
E
K
R
R
L
Q
Rhesus Macaque
Macaca mulatta
XP_001109664
680
76966
P399
L
A
Q
Y
A
S
E
P
S
E
Q
E
L
L
R
Dog
Lupus familis
XP_535797
697
77934
G394
L
V
D
Y
T
S
D
G
I
E
K
R
R
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
P37040
678
77025
P396
L
A
Q
Y
A
S
E
P
S
E
Q
E
H
L
H
Rat
Rattus norvegicus
P00388
678
76944
P396
L
A
Q
Y
A
S
E
P
S
E
Q
E
H
L
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519075
915
101962
A616
L
V
E
H
T
G
D
A
A
E
K
R
R
L
Q
Chicken
Gallus gallus
Q90703
1136
129631
E849
L
S
Q
L
V
T
A
E
G
D
K
Q
R
L
E
Frog
Xenopus laevis
Q6NRG5
600
68059
L346
C
A
A
G
Q
E
E
L
Y
S
Y
C
N
R
P
Zebra Danio
Brachydanio rerio
Q6PFP6
595
66871
H341
A
A
G
Q
D
T
L
H
S
Y
C
N
R
P
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17574
682
76816
P399
L
A
E
S
T
S
D
P
N
E
K
R
R
L
L
Sea Urchin
Strong. purpuratus
XP_787027
728
80257
P458
L
V
E
Y
T
S
D
P
K
E
K
R
R
L
Q
Poplar Tree
Populus trichocarpa
XP_002307336
692
76707
P413
L
A
A
H
A
S
E
P
S
E
A
D
R
L
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_194183
692
76747
P413
L
A
A
Y
A
T
E
P
S
E
A
E
K
L
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
27.3
80.6
N.A.
28.1
27.8
N.A.
56
21.2
28
28.5
N.A.
N.A.
N.A.
31.5
42.9
Protein Similarity:
100
99.1
44.8
87
N.A.
45
44.5
N.A.
65.4
35.9
46.2
44.5
N.A.
N.A.
N.A.
48.4
60.5
P-Site Identity:
100
100
33.3
86.6
N.A.
33.3
33.3
N.A.
73.3
26.6
0
6.6
N.A.
N.A.
N.A.
60
80
P-Site Similarity:
100
100
60
86.6
N.A.
53.3
53.3
N.A.
93.3
53.3
6.6
26.6
N.A.
N.A.
N.A.
66.6
86.6
Percent
Protein Identity:
28.1
N.A.
N.A.
24.8
N.A.
N.A.
Protein Similarity:
47
N.A.
N.A.
44.1
N.A.
N.A.
P-Site Identity:
33.3
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
60
N.A.
N.A.
60
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
58
22
0
36
0
8
8
22
0
15
0
0
0
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% C
% Asp:
0
0
22
0
8
0
43
0
0
8
0
8
0
0
0
% D
% Glu:
0
0
22
0
0
8
43
8
0
79
0
29
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
8
0
8
0
8
8
0
0
0
0
0
0
% G
% His:
0
0
0
15
0
0
0
8
0
0
0
0
15
0
15
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
8
0
50
0
8
0
15
% K
% Leu:
86
0
0
8
0
0
8
8
0
0
0
0
8
86
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
0
8
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
50
0
0
0
0
0
8
8
% P
% Gln:
0
0
29
8
8
0
0
0
0
0
22
8
0
0
36
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
43
65
8
15
% R
% Ser:
0
8
0
8
0
65
0
15
43
8
0
0
0
0
0
% S
% Thr:
0
0
0
0
43
22
0
0
0
0
0
0
0
0
0
% T
% Val:
0
36
0
0
8
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
58
0
0
0
0
8
8
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _