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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
P2RX2
All Species:
7.58
Human Site:
S419
Identified Species:
23.81
UniProt:
Q9UBL9
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBL9
NP_036358.2
471
51754
S419
D
Q
H
P
S
P
P
S
G
Q
E
G
Q
Q
G
Chimpanzee
Pan troglodytes
XP_001164210
404
45295
L361
N
I
G
S
G
L
A
L
L
G
M
A
T
V
L
Rhesus Macaque
Macaca mulatta
XP_001082870
470
51487
S419
D
Q
H
P
S
P
P
S
G
Q
E
G
Q
Q
G
Dog
Lupus familis
XP_848755
463
50830
Q419
A
D
P
S
Q
A
C
Q
A
L
A
V
P
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJX6
388
43419
L345
N
V
G
S
G
L
A
L
L
G
V
A
T
V
L
Rat
Rattus norvegicus
P49653
472
52599
S408
D
Q
P
P
S
P
P
S
G
E
G
P
T
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508992
486
53195
I437
D
L
V
L
I
Y
L
I
K
K
S
H
F
Y
R
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_945334
400
45734
D357
W
I
M
L
T
F
I
D
K
N
E
V
F
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
39.4
96.8
79.8
N.A.
42
79
N.A.
40.7
N.A.
N.A.
46.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
54.3
97.6
83.8
N.A.
57.1
84.1
N.A.
57.2
N.A.
N.A.
60
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
100
0
N.A.
0
60
N.A.
6.6
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
100
0
N.A.
6.6
66.6
N.A.
13.3
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
0
0
0
13
25
0
13
0
13
25
0
0
0
% A
% Cys:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% C
% Asp:
50
13
0
0
0
0
0
13
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
13
38
0
0
0
13
% E
% Phe:
0
0
0
0
0
13
0
0
0
0
0
0
25
0
0
% F
% Gly:
0
0
25
0
25
0
0
0
38
25
13
25
0
0
38
% G
% His:
0
0
25
0
0
0
0
0
0
0
0
13
0
0
0
% H
% Ile:
0
25
0
0
13
0
13
13
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
25
13
0
0
0
0
0
% K
% Leu:
0
13
0
25
0
25
13
25
25
13
0
0
0
13
25
% L
% Met:
0
0
13
0
0
0
0
0
0
0
13
0
0
0
0
% M
% Asn:
25
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% N
% Pro:
0
0
25
38
0
38
38
0
0
0
0
13
13
13
13
% P
% Gln:
0
38
0
0
13
0
0
13
0
25
0
0
25
25
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% R
% Ser:
0
0
0
38
38
0
0
38
0
0
13
0
0
13
0
% S
% Thr:
0
0
0
0
13
0
0
0
0
0
0
0
38
0
0
% T
% Val:
0
13
13
0
0
0
0
0
0
0
13
25
0
25
0
% V
% Trp:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
13
0
0
0
0
0
0
0
13
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _