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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHCR7
All Species:
16.36
Human Site:
S83
Identified Species:
24
UniProt:
Q9UBM7
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBM7
NP_001157289.1
475
54489
S83
V
T
G
H
A
R
L
S
D
I
W
A
K
T
P
Chimpanzee
Pan troglodytes
XP_001174170
475
54471
S83
V
T
G
H
A
R
L
S
D
I
W
A
K
T
P
Rhesus Macaque
Macaca mulatta
XP_001099101
464
52208
S83
A
T
G
R
A
R
L
S
D
I
W
A
K
T
P
Dog
Lupus familis
XP_540796
475
54376
S83
A
T
G
R
A
H
L
S
D
I
W
A
K
T
P
Cat
Felis silvestris
Mouse
Mus musculus
O88455
471
53900
A83
A
S
L
A
D
I
W
A
K
T
P
P
V
T
A
Rat
Rattus norvegicus
Q9Z2Z8
471
54136
A83
A
S
L
A
D
I
W
A
K
T
P
P
V
T
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506255
505
58229
S113
F
T
G
N
N
H
L
S
D
I
W
A
K
T
P
Chicken
Gallus gallus
P23913
637
73480
N138
E
P
D
S
T
E
R
N
D
T
S
S
K
L
L
Frog
Xenopus laevis
Q7ZXH1
473
54804
W84
K
A
R
L
S
D
I
W
D
K
T
P
A
L
T
Zebra Danio
Brachydanio rerio
Q7SXF1
478
55171
F86
Y
N
G
D
A
T
L
F
T
I
W
N
R
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781710
504
58448
L112
M
Q
K
G
A
L
T
L
T
M
L
W
D
Q
M
Poplar Tree
Populus trichocarpa
XP_002316435
434
49833
R63
G
F
I
N
I
W
P
R
P
T
A
I
A
W
K
Maize
Zea mays
NP_001148483
450
51183
M79
G
L
K
A
I
W
P
M
P
T
L
V
A
W
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LDU6
432
49573
R61
G
L
I
N
I
W
P
R
P
T
L
I
A
W
K
Baker's Yeast
Sacchar. cerevisiae
P32462
438
50597
Y66
G
I
K
P
L
R
Y
Y
L
G
N
R
E
L
W
Red Bread Mold
Neurospora crassa
P38670
490
54704
A88
F
G
L
F
S
W
S
A
T
L
W
T
L
G
Y
Conservation
Percent
Protein Identity:
100
99.5
87.7
89.2
N.A.
88
86.7
N.A.
74.2
28.7
75.5
73
N.A.
N.A.
N.A.
N.A.
52.9
Protein Similarity:
100
99.5
90.3
94.9
N.A.
94.5
93.2
N.A.
85.1
42.3
86.1
83.4
N.A.
N.A.
N.A.
N.A.
69
P-Site Identity:
100
100
86.6
80
N.A.
6.6
6.6
N.A.
73.3
13.3
6.6
40
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
86.6
80
N.A.
20
20
N.A.
80
26.6
20
46.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
34.5
34.3
N.A.
33
29.2
30.8
Protein Similarity:
54.1
55.5
N.A.
53.2
46.5
48.7
P-Site Identity:
0
0
N.A.
0
6.6
6.6
P-Site Similarity:
6.6
0
N.A.
6.6
13.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
7
0
19
38
0
0
19
0
0
7
32
25
7
13
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
7
13
7
0
0
44
0
0
0
7
0
0
% D
% Glu:
7
0
0
0
0
7
0
0
0
0
0
0
7
0
0
% E
% Phe:
13
7
0
7
0
0
0
7
0
0
0
0
0
0
0
% F
% Gly:
25
7
38
7
0
0
0
0
0
7
0
0
0
7
0
% G
% His:
0
0
0
13
0
13
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
13
0
19
13
7
0
0
38
0
13
0
0
0
% I
% Lys:
7
0
19
0
0
0
0
0
13
7
0
0
38
0
19
% K
% Leu:
0
13
19
7
7
7
38
7
7
7
19
0
7
19
7
% L
% Met:
7
0
0
0
0
0
0
7
0
7
0
0
0
0
7
% M
% Asn:
0
7
0
19
7
0
0
7
0
0
7
7
0
0
0
% N
% Pro:
0
7
0
7
0
0
19
0
19
0
13
19
0
0
38
% P
% Gln:
0
7
0
0
0
0
0
0
0
0
0
0
0
7
0
% Q
% Arg:
0
0
7
13
0
25
7
13
0
0
0
7
7
0
0
% R
% Ser:
0
13
0
7
13
0
7
32
0
0
7
7
0
0
0
% S
% Thr:
0
32
0
0
7
7
7
0
19
38
7
7
0
44
7
% T
% Val:
13
0
0
0
0
0
0
0
0
0
0
7
13
0
0
% V
% Trp:
0
0
0
0
0
25
13
7
0
0
44
7
0
19
7
% W
% Tyr:
7
0
0
0
0
0
7
7
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _