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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHCR7
All Species:
11.52
Human Site:
T19
Identified Species:
16.89
UniProt:
Q9UBM7
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBM7
NP_001157289.1
475
54489
T19
A
K
S
L
D
G
V
T
N
D
R
T
A
S
Q
Chimpanzee
Pan troglodytes
XP_001174170
475
54471
T19
A
K
S
L
D
G
V
T
N
D
R
T
A
S
Q
Rhesus Macaque
Macaca mulatta
XP_001099101
464
52208
T19
A
K
S
G
D
S
V
T
N
D
R
T
A
S
Q
Dog
Lupus familis
XP_540796
475
54376
A19
T
K
S
P
G
S
I
A
N
S
R
D
E
T
Q
Cat
Felis silvestris
Mouse
Mus musculus
O88455
471
53900
A19
V
K
S
P
N
G
K
A
G
S
Q
G
Q
W
G
Rat
Rattus norvegicus
Q9Z2Z8
471
54136
A19
A
K
N
H
N
V
K
A
E
S
Q
G
Q
W
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506255
505
58229
S49
S
K
N
K
N
G
I
S
D
K
N
K
A
L
Q
Chicken
Gallus gallus
P23913
637
73480
R74
S
S
S
S
S
P
S
R
R
S
R
S
R
S
R
Frog
Xenopus laevis
Q7ZXH1
473
54804
E20
D
K
K
V
A
N
G
E
K
Q
H
V
G
Q
W
Zebra Danio
Brachydanio rerio
Q7SXF1
478
55171
E22
A
N
G
A
Q
T
V
E
K
E
P
S
K
E
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781710
504
58448
G48
P
M
K
R
T
T
N
G
T
S
A
V
D
R
K
Poplar Tree
Populus trichocarpa
XP_002316435
434
49833
Maize
Zea mays
NP_001148483
450
51183
A15
S
A
G
A
K
P
T
A
A
A
P
P
V
T
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LDU6
432
49573
Baker's Yeast
Sacchar. cerevisiae
P32462
438
50597
Red Bread Mold
Neurospora crassa
P38670
490
54704
G24
R
Q
Q
H
Y
E
F
G
G
P
I
G
A
F
G
Conservation
Percent
Protein Identity:
100
99.5
87.7
89.2
N.A.
88
86.7
N.A.
74.2
28.7
75.5
73
N.A.
N.A.
N.A.
N.A.
52.9
Protein Similarity:
100
99.5
90.3
94.9
N.A.
94.5
93.2
N.A.
85.1
42.3
86.1
83.4
N.A.
N.A.
N.A.
N.A.
69
P-Site Identity:
100
100
86.6
33.3
N.A.
20
13.3
N.A.
26.6
20
6.6
13.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
86.6
46.6
N.A.
33.3
33.3
N.A.
66.6
40
13.3
26.6
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
34.5
34.3
N.A.
33
29.2
30.8
Protein Similarity:
54.1
55.5
N.A.
53.2
46.5
48.7
P-Site Identity:
0
0
N.A.
0
0
6.6
P-Site Similarity:
0
13.3
N.A.
0
0
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
32
7
0
13
7
0
0
25
7
7
7
0
32
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
0
19
0
0
0
7
19
0
7
7
0
0
% D
% Glu:
0
0
0
0
0
7
0
13
7
7
0
0
7
7
0
% E
% Phe:
0
0
0
0
0
0
7
0
0
0
0
0
0
7
0
% F
% Gly:
0
0
13
7
7
25
7
13
13
0
0
19
7
0
19
% G
% His:
0
0
0
13
0
0
0
0
0
0
7
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
13
0
0
0
7
0
0
0
0
% I
% Lys:
0
50
13
7
7
0
13
0
13
7
0
7
7
0
7
% K
% Leu:
0
0
0
13
0
0
0
0
0
0
0
0
0
7
0
% L
% Met:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
13
0
19
7
7
0
25
0
7
0
0
0
0
% N
% Pro:
7
0
0
13
0
13
0
0
0
7
13
7
0
0
7
% P
% Gln:
0
7
7
0
7
0
0
0
0
7
13
0
13
7
32
% Q
% Arg:
7
0
0
7
0
0
0
7
7
0
32
0
7
7
7
% R
% Ser:
19
7
38
7
7
13
7
7
0
32
0
13
0
25
0
% S
% Thr:
7
0
0
0
7
13
7
19
7
0
0
19
0
13
0
% T
% Val:
7
0
0
7
0
7
25
0
0
0
0
13
7
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
7
% W
% Tyr:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _