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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHCR7
All Species:
30.91
Human Site:
T463
Identified Species:
45.33
UniProt:
Q9UBM7
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBM7
NP_001157289.1
475
54489
T463
G
R
D
W
E
R
Y
T
A
A
V
P
Y
R
L
Chimpanzee
Pan troglodytes
XP_001174170
475
54471
T463
G
R
D
W
E
R
Y
T
A
A
V
P
Y
R
L
Rhesus Macaque
Macaca mulatta
XP_001099101
464
52208
T452
G
R
D
W
E
R
Y
T
A
A
V
P
Y
R
L
Dog
Lupus familis
XP_540796
475
54376
T463
G
S
D
W
K
R
Y
T
A
A
V
P
H
R
L
Cat
Felis silvestris
Mouse
Mus musculus
O88455
471
53900
T459
G
R
D
W
E
R
Y
T
A
A
V
P
Y
R
L
Rat
Rattus norvegicus
Q9Z2Z8
471
54136
V459
G
R
D
W
E
R
Y
V
A
A
V
P
Y
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506255
505
58229
T493
G
K
D
W
K
R
Y
T
S
A
V
P
K
R
L
Chicken
Gallus gallus
P23913
637
73480
Y614
H
L
L
E
H
S
T
Y
L
I
C
K
L
K
Y
Frog
Xenopus laevis
Q7ZXH1
473
54804
T461
G
K
D
W
K
L
Y
T
S
A
V
P
Y
R
L
Zebra Danio
Brachydanio rerio
Q7SXF1
478
55171
T466
G
K
D
W
E
R
Y
T
A
A
V
S
Y
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781710
504
58448
M492
G
K
S
W
D
L
Y
M
E
K
V
P
C
R
L
Poplar Tree
Populus trichocarpa
XP_002316435
434
49833
E423
K
Y
W
K
L
Y
C
E
K
V
R
Y
R
I
V
Maize
Zea mays
NP_001148483
450
51183
N439
K
Y
W
K
I
Y
C
N
K
V
P
Y
R
V
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LDU6
432
49573
E421
K
Y
W
K
L
Y
C
E
K
V
K
Y
R
I
I
Baker's Yeast
Sacchar. cerevisiae
P32462
438
50597
E426
G
E
N
W
E
E
Y
E
R
K
V
P
Y
K
I
Red Bread Mold
Neurospora crassa
P38670
490
54704
K478
G
D
D
W
E
K
Y
K
K
L
V
K
W
R
I
Conservation
Percent
Protein Identity:
100
99.5
87.7
89.2
N.A.
88
86.7
N.A.
74.2
28.7
75.5
73
N.A.
N.A.
N.A.
N.A.
52.9
Protein Similarity:
100
99.5
90.3
94.9
N.A.
94.5
93.2
N.A.
85.1
42.3
86.1
83.4
N.A.
N.A.
N.A.
N.A.
69
P-Site Identity:
100
100
100
80
N.A.
100
93.3
N.A.
73.3
0
73.3
86.6
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Similarity:
100
100
100
93.3
N.A.
100
93.3
N.A.
93.3
6.6
93.3
93.3
N.A.
N.A.
N.A.
N.A.
60
Percent
Protein Identity:
34.5
34.3
N.A.
33
29.2
30.8
Protein Similarity:
54.1
55.5
N.A.
53.2
46.5
48.7
P-Site Identity:
0
0
N.A.
0
46.6
46.6
P-Site Similarity:
6.6
6.6
N.A.
6.6
66.6
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
44
57
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
19
0
0
0
7
0
7
0
0
% C
% Asp:
0
7
63
0
7
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
7
0
7
50
7
0
19
7
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
75
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
7
0
0
0
7
0
0
0
0
0
0
0
7
0
0
% H
% Ile:
0
0
0
0
7
0
0
0
0
7
0
0
0
13
25
% I
% Lys:
19
25
0
19
19
7
0
7
25
13
7
13
7
13
0
% K
% Leu:
0
7
7
0
13
13
0
0
7
7
0
0
7
0
63
% L
% Met:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
0
0
0
7
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
7
63
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
32
0
0
0
50
0
0
7
0
7
0
19
69
0
% R
% Ser:
0
7
7
0
0
7
0
0
13
0
0
7
0
0
0
% S
% Thr:
0
0
0
0
0
0
7
50
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
7
0
19
75
0
0
7
7
% V
% Trp:
0
0
19
75
0
0
0
0
0
0
0
0
7
0
0
% W
% Tyr:
0
19
0
0
0
19
75
7
0
0
0
19
50
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _