KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HDAC6
All Species:
4.85
Human Site:
S1009
Identified Species:
8.89
UniProt:
Q9UBN7
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBN7
NP_006035.2
1215
131419
S1009
A
T
L
D
Q
T
T
S
E
E
A
P
G
G
T
Chimpanzee
Pan troglodytes
XP_515218
669
71461
V495
A
A
T
L
D
V
A
V
R
R
G
L
S
H
G
Rhesus Macaque
Macaca mulatta
XP_001101619
1229
132810
S1023
A
T
L
D
Q
T
T
S
E
E
A
P
G
G
T
Dog
Lupus familis
XP_855362
1212
132670
Q1018
V
G
G
A
E
V
I
Q
T
S
C
T
D
N
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2V5
1149
125685
S975
N
K
Q
T
T
G
A
S
P
L
Q
G
V
T
A
Rat
Rattus norvegicus
Q569C4
588
63939
I414
D
G
I
L
D
G
Q
I
R
S
A
I
A
T
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519396
803
87971
A629
L
G
D
G
L
P
E
A
A
G
A
M
D
A
H
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080486
1286
140963
V1054
H
E
D
K
L
L
D
V
Q
S
P
G
V
R
I
Zebra Danio
Brachydanio rerio
XP_693858
858
93375
A684
L
K
L
N
P
E
K
A
G
A
G
D
D
T
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121726
1019
114505
M845
E
E
I
E
T
E
K
M
Q
N
K
K
I
A
T
Nematode Worm
Caenorhab. elegans
Q20296
955
106730
V781
C
I
K
T
I
R
E
V
C
A
V
Q
Q
K
Y
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RX28
660
72704
V486
D
G
L
K
K
V
C
V
G
S
M
D
K
S
P
Baker's Yeast
Sacchar. cerevisiae
P53973
706
80051
D532
L
S
S
S
V
I
I
D
N
S
L
D
F
I
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
27.4
97.4
80.6
N.A.
73.9
26.4
N.A.
41.8
N.A.
46.8
38.1
N.A.
N.A.
35.7
33.1
N.A.
Protein Similarity:
100
39
97.9
85.5
N.A.
80.5
35.5
N.A.
51.1
N.A.
62.6
49.8
N.A.
N.A.
53.1
48
N.A.
P-Site Identity:
100
6.6
100
0
N.A.
6.6
13.3
N.A.
6.6
N.A.
0
6.6
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
100
6.6
100
6.6
N.A.
6.6
20
N.A.
13.3
N.A.
6.6
20
N.A.
N.A.
26.6
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.6
20.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
33.9
33.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
8
0
8
0
0
16
16
8
16
31
0
8
16
8
% A
% Cys:
8
0
0
0
0
0
8
0
8
0
8
0
0
0
0
% C
% Asp:
16
0
16
16
16
0
8
8
0
0
0
24
24
0
8
% D
% Glu:
8
16
0
8
8
16
16
0
16
16
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
31
8
8
0
16
0
0
16
8
16
16
16
16
8
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% H
% Ile:
0
8
16
0
8
8
16
8
0
0
0
8
8
8
8
% I
% Lys:
0
16
8
16
8
0
16
0
0
0
8
8
8
8
8
% K
% Leu:
24
0
31
16
16
8
0
0
0
8
8
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
8
0
0
8
8
0
0
0
% M
% Asn:
8
0
0
8
0
0
0
0
8
8
0
0
0
8
0
% N
% Pro:
0
0
0
0
8
8
0
0
8
0
8
16
0
0
8
% P
% Gln:
0
0
8
0
16
0
8
8
16
0
8
8
8
0
8
% Q
% Arg:
0
0
0
0
0
8
0
0
16
8
0
0
0
8
0
% R
% Ser:
0
8
8
8
0
0
0
24
0
39
0
0
8
8
0
% S
% Thr:
0
16
8
16
16
16
16
0
8
0
0
8
0
24
31
% T
% Val:
8
0
0
0
8
24
0
31
0
0
8
0
16
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _