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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HDAC6
All Species:
13.03
Human Site:
Y1156
Identified Species:
23.89
UniProt:
Q9UBN7
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBN7
NP_006035.2
1215
131419
Y1156
Y
Q
V
Y
C
G
R
Y
I
N
G
H
M
L
Q
Chimpanzee
Pan troglodytes
XP_515218
669
71461
A629
A
R
V
L
N
G
E
A
P
P
S
L
G
P
S
Rhesus Macaque
Macaca mulatta
XP_001101619
1229
132810
Y1170
Y
Q
V
Y
C
G
R
Y
I
N
G
H
M
L
Q
Dog
Lupus familis
XP_855362
1212
132670
Y1153
Y
Q
V
Y
C
G
R
Y
I
S
A
H
M
L
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2V5
1149
125685
S1109
S
E
H
P
L
V
L
S
C
V
D
L
S
T
W
Rat
Rattus norvegicus
Q569C4
588
63939
E548
L
A
Q
V
L
H
G
E
T
P
P
S
L
G
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519396
803
87971
S763
S
G
H
P
L
V
L
S
F
T
D
L
S
V
W
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080486
1286
140963
Y1233
Y
Q
V
L
C
G
R
Y
V
S
Q
H
M
L
S
Zebra Danio
Brachydanio rerio
XP_693858
858
93375
S818
S
G
H
P
V
V
L
S
F
A
D
L
S
V
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121726
1019
114505
W979
C
E
S
T
A
E
N
W
I
C
L
Q
C
Y
I
Nematode Worm
Caenorhab. elegans
Q20296
955
106730
A915
L
S
S
S
H
P
M
A
L
S
M
A
D
L
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RX28
660
72704
I620
E
K
F
K
S
G
E
I
P
I
R
P
P
A
K
Baker's Yeast
Sacchar. cerevisiae
P53973
706
80051
R666
E
N
E
S
R
K
P
R
K
K
F
G
R
V
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
27.4
97.4
80.6
N.A.
73.9
26.4
N.A.
41.8
N.A.
46.8
38.1
N.A.
N.A.
35.7
33.1
N.A.
Protein Similarity:
100
39
97.9
85.5
N.A.
80.5
35.5
N.A.
51.1
N.A.
62.6
49.8
N.A.
N.A.
53.1
48
N.A.
P-Site Identity:
100
13.3
100
80
N.A.
0
0
N.A.
0
N.A.
66.6
0
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
100
20
100
86.6
N.A.
6.6
6.6
N.A.
6.6
N.A.
80
6.6
N.A.
N.A.
20
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.6
20.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
33.9
33.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
8
0
0
16
0
8
8
8
0
8
0
% A
% Cys:
8
0
0
0
31
0
0
0
8
8
0
0
8
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
24
0
8
0
0
% D
% Glu:
16
16
8
0
0
8
16
8
0
0
0
0
0
0
0
% E
% Phe:
0
0
8
0
0
0
0
0
16
0
8
0
0
0
0
% F
% Gly:
0
16
0
0
0
47
8
0
0
0
16
8
8
8
0
% G
% His:
0
0
24
0
8
8
0
0
0
0
0
31
0
0
8
% H
% Ile:
0
0
0
0
0
0
0
8
31
8
0
0
0
0
8
% I
% Lys:
0
8
0
8
0
8
0
0
8
8
0
0
0
0
8
% K
% Leu:
16
0
0
16
24
0
24
0
8
0
8
31
8
39
8
% L
% Met:
0
0
0
0
0
0
8
0
0
0
8
0
31
0
0
% M
% Asn:
0
8
0
0
8
0
8
0
0
16
0
0
0
0
0
% N
% Pro:
0
0
0
24
0
8
8
0
16
16
8
8
8
8
8
% P
% Gln:
0
31
8
0
0
0
0
0
0
0
8
8
0
0
16
% Q
% Arg:
0
8
0
0
8
0
31
8
0
0
8
0
8
0
0
% R
% Ser:
24
8
16
16
8
0
0
24
0
24
8
8
24
0
24
% S
% Thr:
0
0
0
8
0
0
0
0
8
8
0
0
0
8
0
% T
% Val:
0
0
39
8
8
24
0
0
8
8
0
0
0
24
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
24
% W
% Tyr:
31
0
0
24
0
0
0
31
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _