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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPAST
All Species:
11.21
Human Site:
S17
Identified Species:
18.97
UniProt:
Q9UBP0
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBP0
NP_055761.2
616
67197
S17
K
K
G
S
G
G
A
S
N
P
V
P
P
R
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_850973
624
68082
G17
K
K
G
S
G
G
G
G
G
S
S
G
S
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9QYY8
614
66438
S17
K
K
G
S
G
G
A
S
P
A
P
A
R
P
P
Rat
Rattus norvegicus
B2RYN7
581
63003
S17
K
K
G
S
G
G
A
S
P
A
P
A
R
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509194
572
63669
K19
R
K
K
K
R
K
K
K
D
N
F
R
L
G
L
Chicken
Gallus gallus
Q5ZK92
613
66247
S17
K
K
G
S
A
G
S
S
S
A
P
P
A
A
G
Frog
Xenopus laevis
Q6AZT2
600
65835
A17
K
K
K
P
V
T
P
A
A
E
T
G
P
G
S
Zebra Danio
Brachydanio rerio
Q6NW58
570
63067
P17
R
G
G
R
A
C
G
P
V
S
D
G
S
A
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8I0P1
758
82731
S45
R
Q
S
T
H
R
S
S
S
A
S
N
V
A
A
Honey Bee
Apis mellifera
XP_393080
682
76301
P18
R
K
Y
G
T
K
S
P
K
K
L
C
V
T
K
Nematode Worm
Caenorhab. elegans
Q8MNV0
512
56883
Sea Urchin
Strong. purpuratus
O61577
516
57575
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SEX2
523
57218
L8
M
V
G
S
S
N
S
L
A
G
L
Q
D
H
L
Baker's Yeast
Sacchar. cerevisiae
P39955
897
100313
T25
R
R
P
Q
Q
P
L
T
D
F
T
E
L
Y
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
94.7
N.A.
92.5
88.9
N.A.
81.1
83.9
71
62.8
N.A.
42.8
46.9
33.7
30.3
Protein Similarity:
100
N.A.
N.A.
95.8
N.A.
93.9
90
N.A.
84.4
88.4
80.8
73.3
N.A.
55.2
62
49.3
46.7
P-Site Identity:
100
N.A.
N.A.
40
N.A.
60
60
N.A.
6.6
46.6
20
6.6
N.A.
6.6
6.6
0
0
P-Site Similarity:
100
N.A.
N.A.
40
N.A.
60
60
N.A.
20
60
26.6
13.3
N.A.
40
26.6
0
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
31
30.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.3
45.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
15
0
22
8
15
29
0
15
8
22
8
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
15
0
8
0
8
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% F
% Gly:
0
8
50
8
29
36
15
8
8
8
0
22
0
15
15
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
43
58
15
8
0
15
8
8
8
8
0
0
0
0
8
% K
% Leu:
0
0
0
0
0
0
8
8
0
0
15
0
15
0
15
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
8
8
0
8
0
0
0
% N
% Pro:
0
0
8
8
0
8
8
15
15
8
22
15
15
15
22
% P
% Gln:
0
8
0
8
8
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
36
8
0
8
8
8
0
0
0
0
0
8
15
8
8
% R
% Ser:
0
0
8
43
8
0
29
36
15
15
15
0
15
8
15
% S
% Thr:
0
0
0
8
8
8
0
8
0
0
15
0
0
8
0
% T
% Val:
0
8
0
0
8
0
0
0
8
0
8
0
15
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _