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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPAST
All Species:
27.58
Human Site:
S245
Identified Species:
46.67
UniProt:
Q9UBP0
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBP0
NP_055761.2
616
67197
S245
P
L
T
H
T
S
N
S
L
P
R
S
K
T
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_850973
624
68082
S253
P
L
T
H
T
S
N
S
L
P
R
S
K
T
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9QYY8
614
66438
S243
P
L
T
H
A
S
N
S
L
P
R
S
K
T
V
Rat
Rattus norvegicus
B2RYN7
581
63003
S210
P
L
T
H
A
S
N
S
L
P
R
S
K
T
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509194
572
63669
S201
P
L
A
H
T
S
N
S
L
P
R
S
K
A
V
Chicken
Gallus gallus
Q5ZK92
613
66247
S242
P
L
T
H
T
S
N
S
L
P
R
S
K
T
V
Frog
Xenopus laevis
Q6AZT2
600
65835
P229
V
P
K
K
K
D
P
P
P
I
T
S
N
S
Y
Zebra Danio
Brachydanio rerio
Q6NW58
570
63067
T198
A
V
S
K
K
K
D
T
L
T
I
T
N
Q
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8I0P1
758
82731
L386
G
S
K
R
P
V
N
L
A
V
A
N
K
S
Q
Honey Bee
Apis mellifera
XP_393080
682
76301
T311
V
P
G
K
R
V
G
T
V
I
S
K
S
Q
T
Nematode Worm
Caenorhab. elegans
Q8MNV0
512
56883
T175
P
V
T
K
K
S
D
T
V
H
P
E
P
P
V
Sea Urchin
Strong. purpuratus
O61577
516
57575
G179
G
G
R
G
G
A
R
G
S
D
K
D
K
N
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SEX2
523
57218
G186
G
A
R
S
S
T
A
G
K
K
G
A
A
S
K
Baker's Yeast
Sacchar. cerevisiae
P39955
897
100313
S460
L
N
S
K
K
V
A
S
N
P
A
L
N
T
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
94.7
N.A.
92.5
88.9
N.A.
81.1
83.9
71
62.8
N.A.
42.8
46.9
33.7
30.3
Protein Similarity:
100
N.A.
N.A.
95.8
N.A.
93.9
90
N.A.
84.4
88.4
80.8
73.3
N.A.
55.2
62
49.3
46.7
P-Site Identity:
100
N.A.
N.A.
100
N.A.
93.3
93.3
N.A.
86.6
100
6.6
6.6
N.A.
13.3
0
26.6
6.6
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
93.3
93.3
N.A.
86.6
100
13.3
40
N.A.
26.6
13.3
53.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
31
30.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.3
45.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
0
15
8
15
0
8
0
15
8
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
15
0
0
8
0
8
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
22
8
8
8
8
0
8
15
0
0
8
0
0
0
0
% G
% His:
0
0
0
43
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
15
8
0
0
0
0
% I
% Lys:
0
0
15
36
29
8
0
0
8
8
8
8
58
0
8
% K
% Leu:
8
43
0
0
0
0
0
8
50
0
0
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
50
0
8
0
0
8
22
8
0
% N
% Pro:
50
15
0
0
8
0
8
8
8
50
8
0
8
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
8
% Q
% Arg:
0
0
15
8
8
0
8
0
0
0
43
0
0
0
8
% R
% Ser:
0
8
15
8
8
50
0
50
8
0
8
50
8
22
0
% S
% Thr:
0
0
43
0
29
8
0
22
0
8
8
8
0
43
22
% T
% Val:
15
15
0
0
0
22
0
0
15
8
0
0
0
0
50
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _