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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPAST
All Species:
20.3
Human Site:
S273
Identified Species:
34.36
UniProt:
Q9UBP0
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBP0
NP_055761.2
616
67197
S273
A
P
S
Y
S
G
L
S
M
V
S
G
V
K
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_850973
624
68082
S281
A
P
S
C
S
G
L
S
M
V
S
G
V
R
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9QYY8
614
66438
S271
A
P
S
C
S
G
L
S
M
V
S
G
A
R
P
Rat
Rattus norvegicus
B2RYN7
581
63003
S238
A
P
S
C
S
G
L
S
M
V
S
G
A
R
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509194
572
63669
S229
A
P
S
C
S
G
L
S
M
F
S
A
G
R
Q
Chicken
Gallus gallus
Q5ZK92
613
66247
S270
T
P
S
Y
S
G
I
S
T
A
S
V
S
R
P
Frog
Xenopus laevis
Q6AZT2
600
65835
S257
N
R
I
P
N
C
T
S
V
P
T
S
A
R
Q
Zebra Danio
Brachydanio rerio
Q6NW58
570
63067
P226
A
S
G
L
N
C
T
P
S
A
A
Q
S
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8I0P1
758
82731
K414
A
V
Q
R
Q
P
A
K
T
A
A
T
P
P
A
Honey Bee
Apis mellifera
XP_393080
682
76301
K339
C
H
R
V
A
P
I
K
P
S
S
T
P
P
S
Nematode Worm
Caenorhab. elegans
Q8MNV0
512
56883
P203
K
V
D
K
A
S
L
P
M
H
Q
N
P
V
N
Sea Urchin
Strong. purpuratus
O61577
516
57575
F207
E
E
G
D
E
K
K
F
D
P
A
G
Y
D
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SEX2
523
57218
Y214
G
K
S
K
R
G
L
Y
E
G
P
D
E
D
L
Baker's Yeast
Sacchar. cerevisiae
P39955
897
100313
K488
V
P
N
S
S
S
K
K
T
S
S
H
P
S
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
94.7
N.A.
92.5
88.9
N.A.
81.1
83.9
71
62.8
N.A.
42.8
46.9
33.7
30.3
Protein Similarity:
100
N.A.
N.A.
95.8
N.A.
93.9
90
N.A.
84.4
88.4
80.8
73.3
N.A.
55.2
62
49.3
46.7
P-Site Identity:
100
N.A.
N.A.
86.6
N.A.
73.3
73.3
N.A.
66.6
46.6
13.3
6.6
N.A.
6.6
6.6
13.3
6.6
P-Site Similarity:
100
N.A.
N.A.
93.3
N.A.
80
80
N.A.
73.3
60
40
26.6
N.A.
13.3
20
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
31
30.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.3
45.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
0
0
0
15
0
8
0
0
22
22
8
22
0
8
% A
% Cys:
8
0
0
29
0
15
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
8
0
0
0
0
8
0
0
8
0
15
0
% D
% Glu:
8
8
0
0
8
0
0
0
8
0
0
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% F
% Gly:
8
0
15
0
0
50
0
0
0
8
0
36
8
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
8
0
8
0
0
0
% H
% Ile:
0
0
8
0
0
0
15
0
0
0
0
0
0
0
0
% I
% Lys:
8
8
0
15
0
8
15
22
0
0
0
0
0
8
8
% K
% Leu:
0
0
0
8
0
0
50
0
0
0
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
43
0
0
0
0
0
0
% M
% Asn:
8
0
8
0
15
0
0
0
0
0
0
8
0
0
8
% N
% Pro:
0
50
0
8
0
15
0
15
8
15
8
0
29
15
22
% P
% Gln:
0
0
8
0
8
0
0
0
0
0
8
8
0
0
29
% Q
% Arg:
0
8
8
8
8
0
0
0
0
0
0
0
0
43
15
% R
% Ser:
0
8
50
8
50
15
0
50
8
15
58
8
15
15
8
% S
% Thr:
8
0
0
0
0
0
15
0
22
0
8
15
0
0
0
% T
% Val:
8
15
0
8
0
0
0
0
8
29
0
8
15
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
15
0
0
0
8
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _