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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPAST
All Species:
23.64
Human Site:
S44
Identified Species:
40
UniProt:
Q9UBP0
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBP0
NP_055761.2
616
67197
S44
G
P
A
P
P
P
E
S
P
H
K
R
N
L
Y
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_850973
624
68082
S52
R
P
A
P
P
P
E
S
P
H
K
R
N
L
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9QYY8
614
66438
S42
G
P
A
P
A
A
G
S
P
P
K
R
N
P
S
Rat
Rattus norvegicus
B2RYN7
581
63003
S42
G
P
A
P
A
P
G
S
P
H
K
R
N
L
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509194
572
63669
R34
L
V
A
W
L
C
R
R
F
S
R
L
L
M
A
Chicken
Gallus gallus
Q5ZK92
613
66247
S49
A
A
A
A
A
A
A
S
P
H
K
R
N
L
Y
Frog
Xenopus laevis
Q6AZT2
600
65835
S41
Q
V
V
L
A
P
P
S
P
H
K
R
N
L
H
Zebra Danio
Brachydanio rerio
Q6NW58
570
63067
T32
G
N
R
L
L
F
Y
T
R
S
L
S
R
V
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8I0P1
758
82731
S109
S
Y
G
G
Y
S
S
S
V
H
K
Q
N
L
Y
Honey Bee
Apis mellifera
XP_393080
682
76301
S59
F
L
D
A
P
Q
P
S
V
H
K
R
N
L
Y
Nematode Worm
Caenorhab. elegans
Q8MNV0
512
56883
S12
S
K
G
P
A
G
S
S
T
Y
D
R
V
A
Q
Sea Urchin
Strong. purpuratus
O61577
516
57575
Y16
N
T
K
M
G
R
E
Y
A
L
L
G
N
Y
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SEX2
523
57218
L23
K
L
A
R
E
Y
A
L
E
G
S
Y
D
T
S
Baker's Yeast
Sacchar. cerevisiae
P39955
897
100313
V64
W
K
A
L
T
T
D
V
L
F
K
Q
T
L
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
94.7
N.A.
92.5
88.9
N.A.
81.1
83.9
71
62.8
N.A.
42.8
46.9
33.7
30.3
Protein Similarity:
100
N.A.
N.A.
95.8
N.A.
93.9
90
N.A.
84.4
88.4
80.8
73.3
N.A.
55.2
62
49.3
46.7
P-Site Identity:
100
N.A.
N.A.
93.3
N.A.
60
86.6
N.A.
6.6
60
53.3
6.6
N.A.
40
53.3
20
13.3
P-Site Similarity:
100
N.A.
N.A.
93.3
N.A.
60
86.6
N.A.
20
60
60
20
N.A.
46.6
53.3
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
31
30.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.3
45.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
58
15
36
15
15
0
8
0
0
0
0
8
8
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
8
0
0
0
8
0
8
0
0
% D
% Glu:
0
0
0
0
8
0
22
0
8
0
0
0
0
0
8
% E
% Phe:
8
0
0
0
0
8
0
0
8
8
0
0
0
0
0
% F
% Gly:
29
0
15
8
8
8
15
0
0
8
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
50
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
8
15
8
0
0
0
0
0
0
0
65
0
0
0
0
% K
% Leu:
8
15
0
22
15
0
0
8
8
8
15
8
8
58
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
8
8
0
0
0
0
0
0
0
0
0
0
65
0
0
% N
% Pro:
0
29
0
36
22
29
15
0
43
8
0
0
0
8
8
% P
% Gln:
8
0
0
0
0
8
0
0
0
0
0
15
0
0
8
% Q
% Arg:
8
0
8
8
0
8
8
8
8
0
8
58
8
0
0
% R
% Ser:
15
0
0
0
0
8
15
65
0
15
8
8
0
0
15
% S
% Thr:
0
8
0
0
8
8
0
8
8
0
0
0
8
8
0
% T
% Val:
0
15
8
0
0
0
0
8
15
0
0
0
8
8
0
% V
% Trp:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
8
8
8
8
0
8
0
8
0
8
43
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _