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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPAST
All Species:
30.61
Human Site:
S583
Identified Species:
51.79
UniProt:
Q9UBP0
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBP0
NP_055761.2
616
67197
S583
E
M
R
N
I
R
L
S
D
F
T
E
S
L
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_850973
624
68082
S591
E
M
R
N
I
R
L
S
D
F
T
E
S
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9QYY8
614
66438
S581
E
M
R
N
I
R
L
S
D
F
T
E
S
L
K
Rat
Rattus norvegicus
B2RYN7
581
63003
S548
E
M
R
N
I
R
L
S
D
F
T
E
S
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509194
572
63669
S539
E
M
R
N
I
R
L
S
D
F
T
E
S
L
K
Chicken
Gallus gallus
Q5ZK92
613
66247
S580
E
M
R
N
I
K
L
S
D
F
T
E
S
L
K
Frog
Xenopus laevis
Q6AZT2
600
65835
S567
E
M
R
N
M
K
Y
S
D
F
L
G
S
L
K
Zebra Danio
Brachydanio rerio
Q6NW58
570
63067
S536
E
M
R
D
I
R
I
S
D
F
L
E
S
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8I0P1
758
82731
Q725
A
M
R
A
I
T
E
Q
D
F
H
S
S
L
K
Honey Bee
Apis mellifera
XP_393080
682
76301
Q649
S
V
R
N
I
T
M
Q
D
F
R
D
S
L
K
Nematode Worm
Caenorhab. elegans
Q8MNV0
512
56883
R480
G
E
K
I
R
K
I
R
A
S
D
F
D
T
A
Sea Urchin
Strong. purpuratus
O61577
516
57575
P484
E
L
N
Q
P
S
T
P
A
D
F
L
L
A
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SEX2
523
57218
M491
I
S
N
D
P
V
A
M
C
D
F
E
E
A
I
Baker's Yeast
Sacchar. cerevisiae
P39955
897
100313
V864
M
I
R
P
I
G
L
V
D
F
K
N
S
L
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
94.7
N.A.
92.5
88.9
N.A.
81.1
83.9
71
62.8
N.A.
42.8
46.9
33.7
30.3
Protein Similarity:
100
N.A.
N.A.
95.8
N.A.
93.9
90
N.A.
84.4
88.4
80.8
73.3
N.A.
55.2
62
49.3
46.7
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
100
93.3
66.6
80
N.A.
53.3
53.3
0
6.6
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
100
100
80
93.3
N.A.
53.3
73.3
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
31
30.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.3
45.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
0
8
0
15
0
0
0
0
15
8
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
0
0
15
0
0
0
0
79
15
8
8
8
0
0
% D
% Glu:
65
8
0
0
0
0
8
0
0
0
0
58
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
79
15
8
0
0
0
% F
% Gly:
8
0
0
0
0
8
0
0
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
8
8
0
8
72
0
15
0
0
0
0
0
0
0
8
% I
% Lys:
0
0
8
0
0
22
0
0
0
0
8
0
0
0
72
% K
% Leu:
0
8
0
0
0
0
50
0
0
0
15
8
8
79
8
% L
% Met:
8
65
0
0
8
0
8
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
15
58
0
0
0
0
0
0
0
8
0
0
0
% N
% Pro:
0
0
0
8
15
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
0
0
0
15
0
0
0
0
0
0
0
% Q
% Arg:
0
0
79
0
8
43
0
8
0
0
8
0
0
0
0
% R
% Ser:
8
8
0
0
0
8
0
58
0
8
0
8
79
0
0
% S
% Thr:
0
0
0
0
0
15
8
0
0
0
43
0
0
8
0
% T
% Val:
0
8
0
0
0
8
0
8
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _