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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPAST
All Species:
38.79
Human Site:
T600
Identified Species:
65.64
UniProt:
Q9UBP0
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBP0
NP_055761.2
616
67197
T600
K
R
S
V
S
P
Q
T
L
E
A
Y
I
R
W
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_850973
624
68082
T608
K
R
S
V
S
P
Q
T
L
E
A
Y
I
R
W
Cat
Felis silvestris
Mouse
Mus musculus
Q9QYY8
614
66438
T598
K
R
S
V
S
P
Q
T
L
E
A
Y
I
R
W
Rat
Rattus norvegicus
B2RYN7
581
63003
T565
K
R
S
V
S
P
Q
T
L
E
A
Y
I
R
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509194
572
63669
T556
K
R
S
V
S
P
Q
T
L
E
A
Y
I
R
W
Chicken
Gallus gallus
Q5ZK92
613
66247
T597
K
R
S
L
S
P
Q
T
L
E
A
Y
I
R
W
Frog
Xenopus laevis
Q6AZT2
600
65835
T584
K
C
S
V
S
H
S
T
L
E
S
Y
I
R
W
Zebra Danio
Brachydanio rerio
Q6NW58
570
63067
T553
K
R
S
V
S
P
Q
T
L
D
Q
Y
V
R
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8I0P1
758
82731
S742
R
R
S
V
A
P
Q
S
L
N
S
Y
E
K
W
Honey Bee
Apis mellifera
XP_393080
682
76301
S666
R
R
S
V
S
P
A
S
L
A
A
Y
E
K
W
Nematode Worm
Caenorhab. elegans
Q8MNV0
512
56883
Q497
T
I
R
P
S
T
S
Q
K
I
M
S
K
L
S
Sea Urchin
Strong. purpuratus
O61577
516
57575
E501
V
S
K
S
V
G
K
E
D
L
V
K
Y
M
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SEX2
523
57218
S508
V
Q
P
S
V
S
S
S
D
I
E
K
H
E
K
Baker's Yeast
Sacchar. cerevisiae
P39955
897
100313
G881
K
P
S
V
S
Q
D
G
L
V
K
Y
E
K
W
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
94.7
N.A.
92.5
88.9
N.A.
81.1
83.9
71
62.8
N.A.
42.8
46.9
33.7
30.3
Protein Similarity:
100
N.A.
N.A.
95.8
N.A.
93.9
90
N.A.
84.4
88.4
80.8
73.3
N.A.
55.2
62
49.3
46.7
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
100
93.3
73.3
80
N.A.
53.3
60
6.6
0
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
100
100
80
93.3
N.A.
86.6
80
6.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
31
30.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.3
45.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
8
0
0
8
50
0
0
0
8
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
15
8
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
8
0
50
8
0
22
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
15
0
0
50
0
0
% I
% Lys:
65
0
8
0
0
0
8
0
8
0
8
15
8
22
8
% K
% Leu:
0
0
0
8
0
0
0
0
79
8
0
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
8
8
8
0
65
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
8
58
8
0
0
8
0
0
0
0
% Q
% Arg:
15
65
8
0
0
0
0
0
0
0
0
0
0
58
0
% R
% Ser:
0
8
79
15
79
8
22
22
0
0
15
8
0
0
8
% S
% Thr:
8
0
0
0
0
8
0
58
0
0
0
0
0
0
0
% T
% Val:
15
0
0
72
15
0
0
0
0
8
8
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
79
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
79
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _