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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPAST
All Species:
18.48
Human Site:
Y212
Identified Species:
31.28
UniProt:
Q9UBP0
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBP0
NP_055761.2
616
67197
Y212
S
K
S
Q
T
D
V
Y
N
D
S
T
N
L
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_850973
624
68082
Y220
S
K
S
Q
T
D
V
Y
N
D
S
T
N
L
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9QYY8
614
66438
Y210
S
K
S
Q
T
D
V
Y
N
E
S
T
N
L
T
Rat
Rattus norvegicus
B2RYN7
581
63003
K177
R
A
R
R
L
Q
A
K
M
M
T
N
L
V
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509194
572
63669
Y168
S
K
S
Q
P
D
V
Y
H
D
S
T
N
L
T
Chicken
Gallus gallus
Q5ZK92
613
66247
Y209
S
K
P
Q
M
E
V
Y
N
D
S
T
N
L
A
Frog
Xenopus laevis
Q6AZT2
600
65835
H196
Q
A
D
I
Q
G
P
H
S
Q
M
E
V
C
S
Zebra Danio
Brachydanio rerio
Q6NW58
570
63067
S165
L
G
N
L
L
S
Q
S
P
A
E
S
S
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8I0P1
758
82731
R353
T
N
E
P
M
K
L
R
V
R
S
S
G
Y
G
Honey Bee
Apis mellifera
XP_393080
682
76301
T278
N
I
G
Q
N
T
C
T
Q
I
P
K
L
R
P
Nematode Worm
Caenorhab. elegans
Q8MNV0
512
56883
N142
A
T
A
P
E
K
K
N
A
A
K
A
K
E
N
Sea Urchin
Strong. purpuratus
O61577
516
57575
P146
R
R
S
E
P
S
K
P
A
N
R
A
P
G
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SEX2
523
57218
W153
K
S
P
Q
D
G
A
W
A
R
G
P
T
T
R
Baker's Yeast
Sacchar. cerevisiae
P39955
897
100313
S427
I
I
K
S
N
A
S
S
P
T
S
S
L
T
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
94.7
N.A.
92.5
88.9
N.A.
81.1
83.9
71
62.8
N.A.
42.8
46.9
33.7
30.3
Protein Similarity:
100
N.A.
N.A.
95.8
N.A.
93.9
90
N.A.
84.4
88.4
80.8
73.3
N.A.
55.2
62
49.3
46.7
P-Site Identity:
100
N.A.
N.A.
93.3
N.A.
86.6
0
N.A.
80
80
0
0
N.A.
6.6
6.6
0
6.6
P-Site Similarity:
100
N.A.
N.A.
93.3
N.A.
93.3
20
N.A.
86.6
86.6
20
20
N.A.
26.6
13.3
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
31
30.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.3
45.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
15
8
0
0
8
15
0
22
15
0
15
0
0
15
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
8
0
8
29
0
0
0
29
0
0
0
0
8
% D
% Glu:
0
0
8
8
8
8
0
0
0
8
8
8
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
8
0
0
15
0
0
0
0
8
0
8
8
8
% G
% His:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% H
% Ile:
8
15
0
8
0
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
8
36
8
0
0
15
15
8
0
0
8
8
8
0
0
% K
% Leu:
8
0
0
8
15
0
8
0
0
0
0
0
22
36
0
% L
% Met:
0
0
0
0
15
0
0
0
8
8
8
0
0
0
8
% M
% Asn:
8
8
8
0
15
0
0
8
29
8
0
8
36
0
15
% N
% Pro:
0
0
15
15
15
0
8
8
15
0
8
8
8
0
8
% P
% Gln:
8
0
0
50
8
8
8
0
8
8
0
0
0
0
0
% Q
% Arg:
15
8
8
8
0
0
0
8
0
15
8
0
0
8
8
% R
% Ser:
36
8
36
8
0
15
8
15
8
0
50
22
8
8
8
% S
% Thr:
8
8
0
0
22
8
0
8
0
8
8
36
8
15
22
% T
% Val:
0
0
0
0
0
0
36
0
8
0
0
0
8
8
8
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
36
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _