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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPAST
All Species:
16.06
Human Site:
Y52
Identified Species:
27.18
UniProt:
Q9UBP0
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBP0
NP_055761.2
616
67197
Y52
P
H
K
R
N
L
Y
Y
F
S
Y
P
L
F
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_850973
624
68082
Y60
P
H
K
R
N
L
Y
Y
F
S
Y
P
L
F
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9QYY8
614
66438
S50
P
P
K
R
N
P
S
S
F
S
S
P
L
V
V
Rat
Rattus norvegicus
B2RYN7
581
63003
Y50
P
H
K
R
N
L
Y
Y
F
S
Y
P
L
V
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509194
572
63669
A42
F
S
R
L
L
M
A
A
R
A
D
R
Q
P
G
Chicken
Gallus gallus
Q5ZK92
613
66247
Y57
P
H
K
R
N
L
Y
Y
F
S
Y
P
L
F
A
Frog
Xenopus laevis
Q6AZT2
600
65835
L49
P
H
K
R
N
L
H
L
F
S
Y
P
L
L
A
Zebra Danio
Brachydanio rerio
Q6NW58
570
63067
E40
R
S
L
S
R
V
P
E
W
L
L
R
V
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8I0P1
758
82731
V117
V
H
K
Q
N
L
Y
V
V
S
F
P
I
I
F
Honey Bee
Apis mellifera
XP_393080
682
76301
I67
V
H
K
R
N
L
Y
I
V
S
F
P
L
I
L
Nematode Worm
Caenorhab. elegans
Q8MNV0
512
56883
K20
T
Y
D
R
V
A
Q
K
F
Q
D
G
Y
E
K
Sea Urchin
Strong. purpuratus
O61577
516
57575
T24
A
L
L
G
N
Y
E
T
S
L
V
Y
Y
Q
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SEX2
523
57218
V31
E
G
S
Y
D
T
S
V
I
F
F
D
G
A
I
Baker's Yeast
Sacchar. cerevisiae
P39955
897
100313
E72
L
F
K
Q
T
L
I
E
H
N
Y
P
N
T
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
94.7
N.A.
92.5
88.9
N.A.
81.1
83.9
71
62.8
N.A.
42.8
46.9
33.7
30.3
Protein Similarity:
100
N.A.
N.A.
95.8
N.A.
93.9
90
N.A.
84.4
88.4
80.8
73.3
N.A.
55.2
62
49.3
46.7
P-Site Identity:
100
N.A.
N.A.
93.3
N.A.
60
93.3
N.A.
0
93.3
73.3
0
N.A.
46.6
60
13.3
6.6
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
60
93.3
N.A.
20
93.3
80
26.6
N.A.
66.6
73.3
20
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
31
30.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.3
45.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
8
8
8
0
8
0
0
0
8
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
8
0
0
0
0
0
15
8
0
0
0
% D
% Glu:
8
0
0
0
0
0
8
15
0
0
0
0
0
8
0
% E
% Phe:
8
8
0
0
0
0
0
0
50
8
22
0
0
22
8
% F
% Gly:
0
8
0
8
0
0
0
0
0
0
0
8
8
0
15
% G
% His:
0
50
0
0
0
0
8
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
8
8
0
0
0
8
15
8
% I
% Lys:
0
0
65
0
0
0
0
8
0
0
0
0
0
0
8
% K
% Leu:
8
8
15
8
8
58
0
8
0
15
8
0
50
15
22
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
65
0
0
0
0
8
0
0
8
0
0
% N
% Pro:
43
8
0
0
0
8
8
0
0
0
0
65
0
8
0
% P
% Gln:
0
0
0
15
0
0
8
0
0
8
0
0
8
8
8
% Q
% Arg:
8
0
8
58
8
0
0
0
8
0
0
15
0
0
0
% R
% Ser:
0
15
8
8
0
0
15
8
8
58
8
0
0
0
0
% S
% Thr:
8
0
0
0
8
8
0
8
0
0
0
0
0
8
0
% T
% Val:
15
0
0
0
8
8
0
15
15
0
8
0
8
15
22
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
8
0
8
0
8
43
29
0
0
43
8
15
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _